3-(甲苯-4-磺酰氨基)-丙酸合成路线 （共 11 条）
反应条件
sodium hydroxide in water T=60 - 70°C; 0.5 h;
参考文献
DeRuiter; Brubaker; Garner; Barksdale; Mayfield
Journal of Pharmaceutical Sciences, 1987 , vol. 76, # 2 p. 149 - 152
参考文献
Holley; Holley
Journal of the American Chemical Society, 1949 , vol. 71, p. 2129
参考文献
Kirmse; Horner
Chemische Berichte, 1956 , vol. 89, p. 1674,1679
Full Text Show Details
Nikolenko
Zhurnal Obshchei Khimii, 1956 , vol. 26, p. 806;engl.Ausg.S.921
参考文献
Kirmse; Horner
Chemische Berichte, 1956 , vol. 89, p. 1674,1679
反应条件
1: KOH; aqueous THF 2: aq. NaOH solution View Scheme
参考文献
Kirmse; Horner
Chemische Berichte, 1956 , vol. 89, p. 1674,1679
反应条件
1: (COCl)2, DMF / CH2Cl2 / 3 h / Ambient temperature 2: tetrahydrofuran; diethyl ether / 4 h / 0 - 20 °C 3: 93 percent / C6H5COOAg, Et3N / tetrahydrofuran / 2 h / Ambient temperature View Scheme
参考文献
Wang, Jianbo; Hou, Yihua
Journal of the Chemical Society - Perkin Transactions 1, 1998 , # 12 p. 1919 - 1923
反应条件
1: (COCl)2, DMF / CH2Cl2 / 3 h / Ambient temperature 2: tetrahydrofuran; diethyl ether / 4 h / 0 - 20 °C View Scheme
参考文献
Wang, Jianbo; Hou, Yihua
Journal of the Chemical Society - Perkin Transactions 1, 1998 , # 12 p. 1919 - 1923
反应条件
dicyclohexyl-carbodiimide in dichloromethane Ambient temperature;
参考文献
Tanner, David; Somfai, Peter
Tetrahedron, 1988 , vol. 44, # 2 p. 613 - 618
反应条件
1: 1.) thionyl chloride / 1.) methanol, 2.) reflux 2: NaH / dimethylformamide / 90 - 100 °C 3: 1.) triflic anhydride, collidine, 2.) H2O / Multistep reaction. Intramolecular <2+2> cycloaddition of keteniminium salt. View Scheme
参考文献
Gobeaux, Benoit; Ghosez, Leon
Heterocycles, 1989 , vol. 28, # 1 p. 29 - 32
参考文献
Wagner; Voigt; Pfeiffer
Pharmazie, 1984 , vol. 39, # 5 p. 315 - 317
