1-环己基-3-苯基-1-丙酮合成路线 （共 21 条）
反应条件
bis(cyclopentadienyl)titanium dichloride; triethyl amine hydrochloride; zinc in dichloromethane Inert atmosphere; chemoselective reaction;
参考文献
Ashfeld, Brandon L.; Kosal, Andrew D.
Organic Letters, 2010 , vol. 12, # 1 p. 44 - 47
参考文献
Mukaiyama,T. et al.
Journal of the American Chemical Society, 1973 , vol. 95, p. 4763 - 4765
反应条件
1: BuLi / tetrahydrofuran / 1.) -78 deg C, 5 min, 2.) -78 deg C, 4 h 2: tetrahydrofuran; diethyl ether / 1.) -78 to 20 deg C, 2.) reflux, 10 h 3: 2 N aq. HCl / tetrahydrofuran; diethyl ether / 10 h / 20 °C View Scheme
参考文献
Katritzky, Alan R.; Zhang, Guifen; Jiang, Jinlong
Journal of Organic Chemistry, 1995 , vol. 60, # 23 p. 7605 - 7611
反应条件
1: 64 percent / Bu3P / tetrahydrofuran / 14 h / 25 °C 2: 55 percent / AIBN, Bu3SnH / benzene / 80 °C View Scheme
参考文献
Boger, Dale L.; Mathvink, Robert J.
Journal of Organic Chemistry, 1992 , vol. 57, # 5 p. 1429 - 1443
反应条件
1: 1) Mg / 1) ether, 2) ether, reflux 2: CrO3, conc. H2SO4 / H2O; acetone / cooling View Scheme
参考文献
Taylor, Stephen K.; Bischoff, David S.; Blankespoor, Curtis L.; Deck, Paul A.; Harvey, Suzanne M.; et al.
Journal of Organic Chemistry, 1990 , vol. 55, # 13 p. 4202 - 4207
反应条件
1: 1) Mg / 1) ether, 2) ether, reflux 2: CrO3, conc. H2SO4 / H2O; acetone / cooling View Scheme
参考文献
Taylor, Stephen K.; Bischoff, David S.; Blankespoor, Curtis L.; Deck, Paul A.; Harvey, Suzanne M.; et al.
Journal of Organic Chemistry, 1990 , vol. 55, # 13 p. 4202 - 4207
反应条件
boron trifluoride diethyl etherate in dichloromethane 0.5 h; Ambient temperature; Further byproducts given;
参考文献
Taylor, Stephen K.; Bischoff, David S.; Blankespoor, Curtis L.; Deck, Paul A.; Harvey, Suzanne M.; et al.
Journal of Organic Chemistry, 1990 , vol. 55, # 13 p. 4202 - 4207
反应条件
N-(1-chloro-2-methylprop-1-enyl)-N,N-dimethylamine; copper(l) iodide 1.) THF, dichloromethane, 0 deg C, 3 h; 2.) 0 deg C, 1 h; Yield given. Multistep reaction;
参考文献
Fujisawa, Tamotsu; Mori, Toshiki; Higuchi, Kazunobu; Sato, Toshio
Chemistry Letters, 1983 , p. 1791 - 1794
反应条件
diethyl ether; cadmium (II) chloride Erwaermen des Reaktionsprodukts mit Cyclohexancarbonylchlorid in Benzol;
参考文献
Charnicki; Data
Journal of the American Pharmaceutical Association (1912-1977), 1956 , vol. 45, p. 65,67
反应条件
nickel Hydrogenation;
参考文献
Mousseron et al.
Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences, 1955 , vol. 241, p. 602
