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乙二醇
甲醛
63148-62-9
MDI
丁酮
二甲基亚砜
碳酸氢钠
471-34-1
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乙二醇
甲醛
63148-62-9
MDI
丁酮
二甲基亚砜
碳酸氢钠
471-34-1
433-48-7
合成路线
(共 13 条)
338-69-2
D-丙氨酸
+
433-48-7
→
反应条件
35455-20-0
+
127-17-3
丙酮酸
反应条件
pyridoxal 5'-phosphate; recombinant Lactobacillus salivarius UCC118 D-amino acid aminotransferase in aq. phosphate buffer T=30°C; pH=7.5; 0.0166667 h; Enzymatic reaction;
参考文献
Kobayashi, Jyumpei; Shimizu, Yasuhiro; Mutaguchi, Yuta; Doi, Katsumi; Ohshima, Toshihisa
Journal of Molecular Catalysis B: Enzymatic, 2013 , vol. 94, p. 15 - 22
433-48-7
→
反应条件
35455-21-1
3-氟-L-丙氨酸
反应条件
(S)-selective ω-transaminase cloned from ochrobactrum anthropi; isopropylamine in aq. phosphate buffer T=37°C; pH=7; 10 h; Enzymatic reaction; Reagent/catalyst;
参考文献
Park, Eul-Soo; Dong, Joo-Young; Shin, Jong-Shik
Organic and Biomolecular Chemistry, 2013 , vol. 11, # 40 p. 6929 - 6933
433-48-7
+
618-36-0
α-苯乙胺
→
反应条件
35523-45-6
氟氘丙氨酸
反应条件
deuterium; palladium hydroxide-on-charcoal; palladium in ethanol; water
参考文献
Merck and Co., Inc.
Patent: US3976689 A1, 1976 ;
392-58-5
2-氟-3-氧-丁酸-1,4-二乙酯
→
反应条件
433-48-7
反应条件
hydrogenchloride T=105°C;
参考文献
Nair; Busch
Journal of Organic Chemistry, 1958 , vol. 23, p. 137
Full Text View citing articles Show Details
Blank et al.
Journal of the Chemical Society, 1955 , p. 2190,2192
Bl. Res. Coun. Israel, 1953 , vol. 3, p. 101
16652-37-2
→
反应条件
433-48-7
+
35455-21-1
3-氟-L-丙氨酸
+
35455-20-0
+
3130-92-5
反应条件
L-lactate dehydrogenase; Bacillus subtilis L-alanine dehydrogenase; β-NADP+ in aq. phosphate buffer T=25°C; pH=7.9;
参考文献
Goncalves, Luciana P. B.; Antunes; Oestreicher, Enrique G.
Organic Process Research and Development, 2006 , vol. 10, # 3 p. 673 - 677
97935-40-5
→
反应条件
433-48-7
反应条件
hydrogenchloride T=80°C; Yield given;
参考文献
Tsushima, Tadahiko; Kawada, Kenji
Tetrahedron Letters, 1985 , vol. 26, # 20 p. 2445 - 2448
392-58-5
2-氟-3-氧-丁酸-1,4-二乙酯
→
反应条件
433-48-7
+
392-47-2
2-氟-3-氧代丁二酸
反应条件
hydrogenchloride; acetic acid T=5°C; 600 h; Yields of byproduct given;
参考文献
Brandaenge, Svante; Dahlman, Olof; Mahlen, Anders; Moerch, Lars
Acta Chemica Scandinavica, Series B: Organic Chemistry and Biochemistry, 1982 , vol. 36, # 1 p. 67 - 70
97643-52-2
→
反应条件
433-48-7
反应条件
benzylviologen cation radical in water T=25°C; cell free extract of Proteus vulgaris (potassium phosphate buffer pH 7.0), Vmax; Equilibrium constant;
参考文献
Schummer, Anita; Yu, Hongtao; Simon, Helmut
Tetrahedron, 1991 , vol. 47, # 43 p. 9019 - 9034
16652-37-2
→
反应条件
433-48-7
+
35455-21-1
3-氟-L-丙氨酸
反应条件
recombinant C-terminally hexahistidine-tagged Rhodotorula gracilis D-amino acid oxidase-Vitreoscilla hemoglobin fusion protein; oxygen; Adenine-flavine dinucleotide; catalase T=25°C; pH=8; 15 h; aq. phosphate bufferEnzymatic reaction; Kinetics; Reagent/catalystConcentrationTime; optical yield given as percent eeenantioselective reaction;
参考文献
Seo, Young-Man; Khang, Yong-Ho; Yun, Hyungdon
Bioscience, Biotechnology and Biochemistry, 2011 , vol. 75, # 4 p. 820 - 822
433-48-7
+
75-08-1
乙硫醇
→
反应条件
51033-95-5
反应条件
sodium hydroxide
参考文献
Bergmann,E.D.; Mielewitz,A.
Journal of the Chemical Society, 1963 , p. 3736 - 3739
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