2,2,2-三氟苯乙酮合成路线 （共 295 条）
参考文献
McGrath; Levine
Journal of the American Chemical Society, 1955 , vol. 77, p. 3656
反应条件
multistep synthesis: facile synthesis of aryl trifluoromethyl ketones;
参考文献
Kerdesky; Basha
Tetrahedron Letters, 1991 , vol. 32, # 18 p. 2003 - 2004
反应条件
gas phase basicity by measuring the proton-transfer equilibrium constant, also of other trifluoroacetophenones;
参考文献
Mishima, Masaaki; Tsuno, Yuho; Fujio, Mizue
Chemistry Letters, 1990 , # 12 p. 2281 - 2284
反应条件
triphenylphosphine 1.) CH2Cl2, -40 deg C, 30 min, 2.) CH2Cl2, from -40 deg C to RT, overnight; Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Morken; Bachand, Patrick C.; Swenson, Dale C.; Burton, Donald J.
Journal of the American Chemical Society, 1993 , vol. 115, # 13 p. 5430 - 5439
反应条件
chlorine; iron(III) chloride
参考文献
Park et al.
Journal of the American Chemical Society, 1951 , vol. 73, p. 709
反应条件
dipotassium peroxodisulfate; sodium chloride in water; acetonitrile T=100°C; 3 h; regioselective reaction;
参考文献
Gu, Liuqun; Lu, Ting; Zhang, Mingyun; Tou, Lijuan; Zhang, Yugen
Advanced Synthesis and Catalysis, 2013 , vol. 355, # 6 p. 1077 - 1082
反应条件
(S,S)-RuCl2(2,2'-bis(di-3,5-xylylphosphino)-1,1'-binaphthyl)(1,1-dianisyl-2-isopropyl-1,2-ethylenediamine); potassium tert-butylate; hydrogen in isopropyl alcohol T=26 - 30°C; P=7600 Torr; 16 h;
参考文献
Ohkuma; Koizumi; Doucet; Pham; Kozawa; Murata; Katayama; Yokozawa; Ikariya; Noyori
Journal of the American Chemical Society, 1998 , vol. 120, # 51 p. 13529 - 13530
反应条件
anhydrous magnesium perchlorate; chiral bis(1,4-dihydronicotinamide) in chloroform; acetonitrile T=50°C; 11 h; influence of the chiral reagent; Product distribution;
参考文献
Bradshaw, Curt W.; Fu, Hong; Shen, Gwo-Jenn; Wong, Chi-Huey
Journal of Organic Chemistry, 1992 , vol. 57, # 5 p. 1526 - 1532
反应条件
hydrogen in toluene T=20°C; Orito reaction; P=750.075 Torr; optical yield given as percent eeenantioselective reaction;
参考文献
Balazsik, Katalin; Szori, Kornel; Szollosi, Gyoergy; Bartok, Mihaly
Catalysis Communications, 2011 , vol. 12, # 15 p. 1410 - 1414
反应条件
hydrogen in toluene T=20°C; Orito reaction; P=750.075 Torr; optical yield given as percent eeenantioselective reaction;
参考文献
Balazsik, Katalin; Szori, Kornel; Szollosi, Gyoergy; Bartok, Mihaly
Catalysis Communications, 2011 , vol. 12, # 15 p. 1410 - 1414
