2,2,2-三氟苯乙酮合成路线 (共 295 条)
反应条件
cesium fluoride in diethylene glycol dimethyl ether T=25°C; 4 h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Kremlev, M. M.; Maznyi, I. S.; Yagupol'skii, L. M.
Journal of Organic Chemistry USSR (English Translation), 1991 , vol. 27, # 1.2 p. 105 - 108
Zhurnal Organicheskoi Khimii, 1991 , vol. 27, # 1 p. 121 - 124
反应条件
NaHCO3 - Na2CO3 buffer in water; isopropyl alcohol T=50°C; Rate constant;
参考文献
Chipman, David M.; Yaniv, Ruth; Eikeren, Paul van
Journal of the American Chemical Society, 1980 , vol. 102, # 9 p. 3244 - 3246
反应条件
NaHCO3 - Na2CO3 buffer in water; isopropyl alcohol T=50°C; Rate constant;
参考文献
Chipman, David M.; Yaniv, Ruth; Eikeren, Paul van
Journal of the American Chemical Society, 1980 , vol. 102, # 9 p. 3244 - 3246
反应条件
water; triethylamine in benzene 8 h; Heating;
参考文献
Vovk, M. V.; Dorokhov, V. I.; Samarai, L. I.
Journal of Organic Chemistry USSR (English Translation), 1988 , vol. 24, # 4 p. 654 - 658
Zhurnal Organicheskoi Khimii, 1988 , vol. 24, # 4 p. 727 - 732
反应条件
hydroxide in water T=25°C; var. conc. of OH-; Rate constantEquilibrium constant;
参考文献
Guthrie, J. Peter; Barker, Jonathan A.
Journal of the American Chemical Society, 1998 , vol. 120, # 27 p. 6698 - 6703
反应条件
in diethyl ether T=-40°C; 5 h;
参考文献
Watanabe, Shoji; Fujita, Tsutomu; Sakamoto, Masami; Hamano, Hiroyuki; Kitazume, Tomoya; Yamazaki, Takashi
Journal of Fluorine Chemistry, 1997 , vol. 83, # 1 p. 15 - 19
反应条件
2,6-dimethylpyridine; water in various solvent(s) T=25°C; Kinetics;
参考文献
Creary, Xavier; Willis, Elizabeth D.; Gagnon, Madeleine
Journal of the American Chemical Society, 2005 , vol. 127, # 51 p. 18114 - 18120
反应条件
1: CsF / neat (no solvent) / 1 h / 25 °C 2: HCl / H2O / 3 h View Scheme
参考文献
Singh, Rajendra P.; Cao, Ganfeng; Kirchmeier, Robert L.; Shreeve, Jean'ne M.
Journal of Organic Chemistry, 1999 , vol. 64, # 8 p. 2873 - 2876
反应条件
iodine equimolar amount of I2;
参考文献
Kim, Yong-Joo; Osakada, Kohtaro; Yamamoto, Akio
Bulletin of the Chemical Society of Japan, 1989 , vol. 62, # 3 p. 964 - 966
反应条件
n-butyllithium in tetrahydrofuran; hexane T=-78°C; 2.5 h; Inert atmosphere;
参考文献
Hyster, Todd K.; Ruhl, Kyle E.; Rovis, Tomislav
Journal of the American Chemical Society, 2013 , vol. 135, # 14 p. 5364 - 5367