3-(4-甲基苯基)吡啶合成路线 （共 66 条）
反应条件
sodium hydroxide; [[(t-Bu)2P(OH)(t-Bu)2PO]PdCl2]
T=135°C; 24 h;
参考文献
Wolf, Christian; Lerebours, Rachel
Organic Letters, 2004 , vol. 6, # 7 p. 1147 - 1150
反应条件
1: p-methylphenylboronic acid T=75°C; 1 h; dehydrationvacuum;
2: 3-(N,N-diethylcarbamoyloxy)-pyridine With potassium phosphate; NiCl2(PCy3)2; PCy3∙HBF4 in o-xylene
T=150°C; Suzuki-Miyaura coupling; 5 h; Inert atmosphere;
参考文献
Antoft-Finch, Aurora; Blackburn, Tom; Snieckus, Victor
Journal of the American Chemical Society, 2009 , vol. 131, # 49 p. 17750 - 17752
反应条件
magnesium in tetrahydrofuran
参考文献
Benniston, Andrew C.; Farrugia, Louis J.; Mackie, Philip R.; Mallinson, Paul; Clegg, William; Teat, Simon J.
Australian Journal of Chemistry, 2000 , vol. 53, # 8 p. 707 - 713
反应条件
(1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium carbonate in tetrahydrofuran; water
T=40°C; 6 h;
参考文献
Srogl, Jiri; Allred, Gary D.; Liebeskind, Lanny S.
Journal of the American Chemical Society, 1997 , vol. 119, # 50 p. 12376 - 12377
反应条件
C4H6Cl2N2Ni; C33H27NP2 in tetrahydrofuran
T=20°C; Kumada-Corriu reaction; 3 h; Inert atmosphere;
参考文献
Ghosh, Raju; Sarkar, Amitabha
Journal of Organic Chemistry, 2010 , vol. 75, # 23 p. 8283 - 8286
反应条件
tetrabutyl ammonium fluoride in tetrahydrofuran
T=20°C; 16 h;
参考文献
Le Notre, Jerome; Firet, Judith J.; Sliedregt, Leo A. J. M.; Van Steen, Bart J.; Van Koten, Gerard; Gebbink, Robertus J. M. Klein
Organic Letters, 2005 , vol. 7, # 3 p. 363 - 366
反应条件
potassium carbonate; cyclopallated ferrocenylimine c in water; N,N-dimethyl-formamide
T=110°C; Suzuki cross-coupling reaction; 13 h;
参考文献
Zhang, Jinli; Zhao, Liang; Song, Maoping; Mak, Thomas C.W.; Wu, Yangjie
Journal of Organometallic Chemistry, 2006 , vol. 691, # 6 p. 1301 - 1306
反应条件
potassium carbonate; cyclopallated ferrocenylimine c in water; N,N-dimethyl-formamide
T=110°C; Suzuki cross-coupling reaction; 6 h;
参考文献
Zhang, Jinli; Zhao, Liang; Song, Maoping; Mak, Thomas C.W.; Wu, Yangjie
Journal of Organometallic Chemistry, 2006 , vol. 691, # 6 p. 1301 - 1306
反应条件
2,2'-bis(di-p-tolyl-phosphino)-1,1'-binaphthyl; copper(I) oxide; 1,10-phenanthroline; palladium (II) bromide in 1-methyl-pyrrolidin-2-one
T=50 - 190°C; Microwave irradiationInert atmosphere;
参考文献
Goossen, Lukas J.; Linder, Christophe; Rodriguez, Nuria; Lange, Paul P.
Chemistry - A European Journal, 2009 , vol. 15, # 37 p. 9336 - 9349
反应条件
caesium carbonate; cyclopallated ferrocenylimine c in water; N,N-dimethyl-formamide
T=110°C; Suzuki cross-coupling reaction; 24 h;
参考文献
Zhang, Jinli; Zhao, Liang; Song, Maoping; Mak, Thomas C.W.; Wu, Yangjie
Journal of Organometallic Chemistry, 2006 , vol. 691, # 6 p. 1301 - 1306
