3-(4-甲基苯基)吡啶合成路线 （共 66 条）
反应条件
1: With palladium diacetate; xantphos in N-dodecane; butan-1-ol
T=25°C; Suzuki-Miyaura Coupling; 0.0833333 h; Inert atmosphereGlovebox;
2: With cesium hydroxide monohydrate in N-dodecane; water; butan-1-ol
T=80°C; Suzuki-Miyaura Coupling; 4 h; Inert atmosphereGlovebox;
参考文献
Yang, Junfeng; Liu, Sijia; Zheng, Jian-Feng; Zhou, Jianrong
European Journal of Organic Chemistry, 2012 , # 31 p. 6248 - 6259,12
Title/Abstract Full Text Show Details
Yang, Junfeng; Liu, Sijia; Zheng, Jian-Feng; Zhou, Jianrong
European Journal of Organic Chemistry, 2012 , # 31 p. 6248 - 6259
反应条件
caesium carbonate; 1,4-di(diphenylphosphino)-butane; palladium diacetate in ethylene glycol dimethyl ether; water
T=50°C; 24 h;
参考文献
Batey, Robert A; Quach, Tan D
Tetrahedron Letters, 2001 , vol. 42, # 52 p. 9099 - 9103
反应条件
NiClCpIMes in diethyl ether
T=20°C; Grignard cross-coupling reaction; 8 h;
参考文献
Macklin, Todd K.; Snieckus, Victor
Organic Letters, 2005 , vol. 7, # 13 p. 2519 - 2522
反应条件
NiCl2[(4-MeOPh)3P]2; K3PO4*3H2O; tris(4-methoxyphenyl)-phosphine in toluene
T=110°C; 8 h; Inert atmosphere;
参考文献
Chen, Xiaofeng; Ke, Haihua; Zou, Gang
ACS Catalysis, 2014 , vol. 4, # 2 p. 379 - 385
反应条件
triethylamine; palladium diacetate in ethanol
T=80°C; Suzuki-Miyaura cross-coupling; 5 h;
参考文献
Zhang, Liang; Meng, Tianhao; Wu, Jie
Journal of Organic Chemistry, 2007 , vol. 72, # 24 p. 9346 - 9349
反应条件
bis(acetylacetonate)nickel(II); IPr*HBF4 in tetrahydrofuran
T=20°C; Inert atmosphere;
参考文献
Kim, Chul-Bae; Jo, Hyunjong; Ahn, Bo-Kyoung; Kim, Chang Keun; Park, Kwangyong
Journal of Organic Chemistry, 2009 , vol. 74, # 24 p. 9566 - 9569
反应条件
morpholine; C31H45Cl2N3OPd; caesium carbonate in water
T=110°C; Suzuki-Miyaura Coupling; 12 h; Inert atmosphere;
参考文献
Wang, Zhan-Yong; Ma, Qin-Na; Li, Ren-Hao; Shao, Li-Xiong
Organic and Biomolecular Chemistry, 2013 , vol. 11, # 45 p. 7899 - 7906
反应条件
PEG 4000; palladium diacetate; potassium carbonate
T=120°C; 12 h;
参考文献
Wang, Liang; Zhang, Yuhong; Liu, Leifang; Wang, Yanguang
Journal of Organic Chemistry, 2006 , vol. 71, # 3 p. 1284 - 1287
反应条件
1,1'-bis-(diphenylphosphino)ferrocene; [NiCl2(1,2-dimethoxyethane)]; caesium carbonate; zinc; tri-cyclo-hexyl-phosphine in ethylene glycol dimethyl ether; N,N-dimethyl-formamide
T=20 - 75°C; Suzuki-Miyaura cross-coupling reaction; 24 h; Inert atmosphere; chemoselective reaction;
参考文献
Tang, Shi; Takeda, Masahide; Nakao, Yoshiaki; Hiyama, Tamejiro
Chemical Communications, 2011 , vol. 47, # 1 p. 307 - 309
反应条件
tetrabutyl ammonium fluoride; palladium diacetate; 2-(dicyclohexylphosphino)-2',4',6'-tri-i-propyl-1,1’-biphenyl in tetrahydrofuran; tert-butyl alcohol
T=90°C; Hiyama coupling; Inert atmosphere;
参考文献
Zhang, Liang; Qing, Jiang; Yang, Pengyuan; Wu, Jie
Organic Letters, 2008 , vol. 10, # 21 p. 4971 - 4974
