3-(4-甲基苯基)吡啶合成路线 （共 66 条）
反应条件
bis(η3-allyl-μ-chloropalladium(II)); tri-tert-butyl phosphine; potassium hydroxide in water; toluene; tert-butyl alcohol
T=80°C;
参考文献
Boehner, Christine M.; Frye, Elizabeth C.; O'Connell, Kieron M. G.; Galloway, Warren R. J. D.; Sore, Hannah F.; Dominguez, Patricia Garcia; Norton, David; Hulcoop, David G.; Owen, Martin; Turner, Gillian; Crawford, Claire; Horsley, Helen; Spring, David R.
Chemistry - A European Journal, 2011 , vol. 17, # 47 p. 13230 - 13239
反应条件
palladium diacetate; potassium carbonate in dimethyl sulfoxide
T=60°C; Suzuki Coupling; Inert atmosphere;
参考文献
Liu, Jin-Biao; Yan, Hui; Chen, Hui-Xuan; Luo, Yu; Weng, Jiang; Lu, Gui
Chemical Communications, 2013 , vol. 49, # 46 p. 5268 - 5270
反应条件
tetrakis(triphenylphosphine) palladium(0); sodium carbonate in 1,4-dioxane
Suzuki cross-coupling reaction; 16 h; Heating;
参考文献
Cioffi, Christopher L.; Spencer, William T.; Richards, Justin J.; Herr, R. Jason
Journal of Organic Chemistry, 2004 , vol. 69, # 6 p. 2210 - 2212
反应条件
tetrakis(triphenylphosphine) palladium(0); sodium carbonate in 1,4-dioxane
Suzuki cross-coupling reaction; 16 h; Heating;
参考文献
Cioffi, Christopher L.; Spencer, William T.; Richards, Justin J.; Herr, R. Jason
Journal of Organic Chemistry, 2004 , vol. 69, # 6 p. 2210 - 2212
反应条件
1: 85 percent / Et3N / toluene / 12 h / Heating
2: 78 percent / NiClCpIMes / diethyl ether / 8 h / 20 °C
View Scheme
参考文献
Macklin, Todd K.; Snieckus, Victor
Organic Letters, 2005 , vol. 7, # 13 p. 2519 - 2522
反应条件
1: 2.) NH4PF6 / 1.) MTBE, 23 deg C, 2.) acetone, 23 deg C
2: 77 percent / Pd(dppf)Cl2, K2CO3*H2O / tetrahydrofuran; H2O / 6 h / 40 °C
View Scheme
参考文献
Srogl, Jiri; Allred, Gary D.; Liebeskind, Lanny S.
Journal of the American Chemical Society, 1997 , vol. 119, # 50 p. 12376 - 12377
反应条件
C52H44CoN4O4; potassium hydroxide; tert-butyl alcohol
T=200°C; 10 h; Inert atmosphereDarkness;
参考文献
Qian, Ying Ying; Wong, Ka Lai; Zhang, Meng Wen; Kwok, Tsz Yiu; To, Ching Tat; Chan, Kin Shing
Tetrahedron Letters, 2012 , vol. 53, # 13 p. 1571 - 1575
反应条件
potassium hydroxide; tetrakis(triphenylphosphine) palladium(0); tetrabutylammomium bromide in tetrahydrofuran
2 h; Heating;
参考文献
Ishikura, Minoru; Kamada, Machiko; Terashima, Masanao
Heterocycles, 1984 , vol. 22, # 2 p. 265 - 268
反应条件
1,10-phenanthroline; palladium diacetate; caesium carbonate
T=140°C; 48 h; Sealed tube;
参考文献
Ye, Mengchun; Gao, Guo-Lin; Edmunds, Andrew J. F.; Worthington; Morris, James A.; Yu, Jin-Quan
Journal of the American Chemical Society, 2011 , vol. 133, # 47 p. 19090 - 19093
反应条件
1.1: n-butyllithium / diethyl ether / 2 h / -78 °C
1.2: 3 h / -78 °C
2.1: C52H67ClFeNPPd; copper(l) iodide; cesium fluoride / N,N-dimethyl-formamide / 12 h / 110 °C / |Inert atmosphere
View Scheme
参考文献
Ma, Gaizhi; Leng, Yuting; Wu, Yusheng; Wu, Yangjie
Tetrahedron, 2013 , vol. 69, # 2 p. 902 - 909
