1,2,4-三苯基-1,4-丁二酮合成路线 （共 63 条）
反应条件
neodymium in N,N-dimethyl acetamide
Irradiation;
参考文献
Li, Zhi-Fang; Tomisaka, Yuri; Nomoto, Akihiro; Zhang, Yongmin; Ogawa, Akiya
Chemistry Letters, 2009 , vol. 38, # 1 p. 16 - 17
反应条件
3-ethyl-5-(2-hydroxyethyl)-4-methyl-1,3-thiazolium bromide; 1,8-diazabicyclo[5.4.0]undec-7-ene; isopropyl alcohol in tetrahydrofuran
T=70°C; Sila-Stetter reaction; 24 h; Product distribution; Further Variations:ReagentsSolvents;
参考文献
Mattson, Anita E.; Bharadwaj, Ashwin R.; Zuhl, Andrea M.; Scheidt, Karl A.
Journal of Organic Chemistry, 2006 , vol. 71, # 15 p. 5715 - 5724
反应条件
3-ethyl-5-(2-hydroxyethyl)-4-methyl-1,3-thiazolium bromide; 1,8-diazabicyclo[5.4.0]undec-7-ene; isopropyl alcohol in tetrahydrofuran
T=70°C; 24 h;
参考文献
Mattson, Anita E.; Bharadwaj, Ashwin R.; Zuhl, Andrea M.; Scheidt, Karl A.
Journal of Organic Chemistry, 2006 , vol. 71, # 15 p. 5715 - 5724
反应条件
copper; zinc; bis-triphenylphosphine-palladium(II) chloride in ethylene glycol dimethyl ether
T=65°C; 5 h;
参考文献
Tamaru, Yoshinao; Ochiai, Hirofumi; Yoshida, Zen-ichi
Tetrahedron Letters, 1984 , vol. 25, # 35 p. 3861 - 3864
反应条件
triethylamine; 3,4-dimethyl-1,3-thiazol-3-ium iodide functionalized ROMPgel in N,N-dimethyl-formamide
T=80°C; Stetter reaction; 22 h;
参考文献
Barrett, Anthony G. M.; Love, Andrew C.; Tedeschi, Livio
Organic Letters, 2004 , vol. 6, # 19 p. 3377 - 3380
反应条件
carbon monoxide; copper; zinc; bis(cyclopentadienyl)titanium dichloride; bis-triphenylphosphine-palladium(II) chloride in ethylene glycol dimethyl ether
T=65°C; 5 h;
参考文献
Tamaru, Yoshinao; Ochiai, Hirofumi; Yoshida, Zen-ichi
Tetrahedron Letters, 1984 , vol. 25, # 35 p. 3861 - 3864
反应条件
samarium in N,N-dimethyl-formamide
T=25°C; Michael addition; 1.5 h; Inert atmosphere;
参考文献
Liu, Yongjun; Li, Yuanying; Qi, Yan; Wan, Jun
Synthesis, 2010 , # 24 art. no. F12610SS, p. 4188 - 4192
反应条件
bis(diethylamino)cyclopropenium tetraphenylborate; 1,8-diazabicyclo[5.4.0]undec-7-ene in dichloromethane
T=20°C; Stetter 1,4-Dicarbonyl Synthesis; Inert atmosphereSchlenk technique;
参考文献
Wilde, Myron M. D.; Gravel, Michel
Angewandte Chemie - International Edition, 2013 , vol. 52, # 48 p. 12651 - 12654
Angew. Chem., 2013 , vol. 125, # 48 p. 12883 - 12886
反应条件
1: 55 percent / NaOH / TEBAC / dimethylsulfoxide / 6 h / 35 °C
2: conc.HCl / ethanol / 0.17 h / Heating
View Scheme
参考文献
Zdrojewski, T.; Jonczyk, A.
Synthesis, 1990 , # 3 p. 224 - 233
反应条件
1: NaOH, tetraalkylammonium halide / dimethylsulfoxide
2: aq. HCl
View Scheme
参考文献
Jonczyk, Andrzej; Lipiak, Dariusz; Stepniewski, Pawel; Zdrojewski, Tadeusz
Bulletin des Societes Chimiques Belges, 1988 , vol. 97, # 2 p. 165 - 166
