in methanol T=20°C; 1 h;

1: 4,6-dichloropyrimidine-2-(methylthio)pyrimidine With lithium diisopropyl amide in tetrahydrofuran T=-78°C; 1.5 h; 2: 1-piperidinecarboxaldehyde in tetrahydrofuran 0.166667 h;