反应条件
1: mercapto acetic acid ethylester With sodium hydride in N,N-dimethyl-formamide
T=20°C; 0.5 h;
2: ortho-fluorobenzaldehyde in N,N-dimethyl-formamide
18 h; Reflux;
参考文献
Matthews, Jay M.; Qin, Ning; Colburn, Raymond W.; Dax, Scott L.; Hawkins, Mike; McNally, James J.; Reany, Laura; Youngman, Mark A.; Baker, Judith; Hutchinson, Tasha; Liu, Yi; Lubin, Mary Lou; Neeper, Michael; Brandt, Michael R.; Stone, Dennis J.; Flores, Christopher M.
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 8 p. 2922 - 2926