1-(5-乙基-2,4-二羟基苯基)乙酮合成路线 （共 17 条）
反应条件
potassium carbonate; potassium iodide in butanone 30 h;
参考文献
Liu, Peng; Xu, Xing; Chen, Lili; Ma, Lei; Shen, Xu; Hu, Lihong
Bioorganic and Medicinal Chemistry, 2014 , vol. 22, # 5 p. 1596 - 1607
反应条件
potassium iodide; potassium carbonate in dimethyl sulfoxide
参考文献
Bristol-Myers Squibb Pharma Company
Patent: EP1293214 A2, 2003 ;
反应条件
zinc(II) chloride
T=95 - 100°C; 6 h;
参考文献
Liu, Peng; Xu, Xing; Chen, Lili; Ma, Lei; Shen, Xu; Hu, Lihong
Bioorganic and Medicinal Chemistry, 2014 , vol. 22, # 5 p. 1596 - 1607
反应条件
acetic acid; zinc(II) chloride
T=140°C;
参考文献
Weiss; Kratz
Monatshefte fuer Chemie, 1929 , vol. 51, p. 391
反应条件
1: Zn; HgCl2; conc. HCl / H2O / 5 h / Heating
2: ZnCl2 / 3.5 h / 110 °C
View Scheme
参考文献
Nair; Shah; Baluja; Chanda
Medicinal Chemistry Research, 2002 , vol. 11, # 8 p. 463 - 479
反应条件
1: ZnCl2 / 3 h / 110 °C
2: Zn; HgCl2; conc. HCl / H2O / 5 h / Heating
3: ZnCl2 / 3.5 h / 110 °C
View Scheme
参考文献
Nair; Shah; Baluja; Chanda
Medicinal Chemistry Research, 2002 , vol. 11, # 8 p. 463 - 479
反应条件
aluminium trichloride
参考文献
Rosenmund; Buchwald; Deligiannis
Archiv der Pharmazie (Weinheim, Germany), 1933 , vol. 271, p. 342,348
反应条件
aluminium trichloride; nitrobenzene
参考文献
Rosenmund; Buchwald; Deligiannis
Archiv der Pharmazie (Weinheim, Germany), 1933 , vol. 271, p. 342,348
反应条件
pyridine hydrochloride
参考文献
Royer,R. et al.
Bulletin de la Societe Chimique de France, 1965 , p. 2607 - 2616
反应条件
1: CrO3
2: Py*HCl
View Scheme
参考文献
Royer,R. et al.
Bulletin de la Societe Chimique de France, 1965 , p. 2607 - 2616
