2,4,5-三甲氧基苯甲醛合成路线 （共 90 条）
反应条件
aus Oxyhydrochinontrimethylaether;
参考文献
Szeki
Chemische Berichte, 1911 , vol. 44, p. 1479
反应条件
1: AlCl3, aluminium chloride / dichloromethane / 20 °C / Reflux 2: pyridine; aniline / 24 h / 20 °C 3: pyridine / ethylene glycol / Reflux View Scheme
参考文献
Cai, Xueting; Yang, Jie; Zhou, Jinpei; Lu, Wuguang; Hu, Chunping; Gu, Zhenhua; Huo, Jiege; Wang, Xiaoning; Cao, Peng
Bioorganic and Medicinal Chemistry, 2013 , vol. 21, # 1 p. 84 - 92
反应条件
argentic oxide; water; nitric acid; sodium hydrogensulfite Product distribution;
参考文献
Ruiz, V. M.; Tapia, R.; Valderrama, J.; Vega, J. C.
Journal of Heterocyclic Chemistry, 1981 , vol. 18, p. 1161 - 1164
反应条件
1: 85.3 percent / 50percent aq. KOH / ethanol / 24 h / Ambient temperature 2: thallium nitrate / CHCl3 / Ambient temperature 3: H2, triethylamine / 10percent Pd/C / ethyl acetate / 760 Torr / Ambient temperature 4: 5percent HCl / methanol / 2 h / Heating View Scheme
参考文献
Bioscience, Biotechnology, and Biochemistry, , vol. 57, # 1 p. 107 - 114
反应条件
1: 92 percent / t-BuOK / 2-methyl-propan-2-ol / 0.67 h / Heating 2: 81 percent / Ac2O / 0.75 h / Heating View Scheme
参考文献
Tetrahedron, , vol. 61, # 3 p. 555 - 564
反应条件
1: mCPBA / 2 h / Ambient temperature 2: aq. KOH / ethanol / 2 h / 50 °C 3: 94 percent / NaH / dimethylformamide / 1 h / Ambient temperature View Scheme
参考文献
Filosa, Rosanna; Peduto, Antonella; Aparoy, Polamarasetty; Schaible, Anja M.; Luderer, Susann; Krauth, Verena; Petronzi, Carmen; Massa, Antonio; De Rosa, Mario; Reddanna, Pallu; Werz, Oliver
European Journal of Medicinal Chemistry, 2013 , vol. 67, p. 269 - 279
反应条件
sodium tetrahydroborate in methanol 0.5 h;
参考文献
Witiak; Loper; Ananthan; Almerico; Verhoef; Filppi
Journal of Medicinal Chemistry, 1989 , vol. 32, # 7 p. 1636 - 1642
反应条件
1: (ethyl)-triphenylphosphonium bromide With n-butyllithium in tetrahydrofuran T=-78 - 0°C; Inert atmosphere; 2: 2,4,5-trimethoxybenzaldehyde in tetrahydrofuran T=-78 - 25°C; Wittig reaction; 3.83333 h; Inert atmosphere; 3: With dichloro bis(acetonitrile) palladium(II) in chloroform T=25°C; 72 h;
参考文献
Green, Ivan R.; October, Natasha
Arkivoc, 2010 , vol. 2010, # 2 p. 71 - 96
反应条件
potassium carbonate in 1,4-dioxane Wittig reaction; 24 h; Heating; Title compound not separated from byproducts.;
参考文献
Green, Ivan R.; October, Natasha
Arkivoc, 2010 , vol. 2010, # 2 p. 71 - 96
反应条件
1: With potassium carbonate in 1,4-dioxane Wittig reaction; 24 h; Heating; 2: With dichloro bis(acetonitrile) palladium(II) in dichloromethane T=20°C; 24 h; Further stages.;
参考文献
Xu, Guangyu; Zhou, Yi; Zuo, Gaolei; Jiang, Yongjun
Organic Preparations and Procedures International, 2007 , vol. 39, # 5 p. 514 - 517
