4-吗啉-2-丁炔-1-醇合成路线 （共 5 条）
反应条件
triethylamine in benzene
参考文献
Willette; Driscoll
Journal of medicinal chemistry, 1972 , vol. 15, # 1 p. 110 - 112
反应条件
formaldehyd; potassium iodide in ethanol; water; ethyl acetate
参考文献
Fujisawa Pharmaceutical Co., Ltd.
Patent: US6087357 A1, 2000 ;
反应条件
copper diacetate; iron(III) chloride in 1,4-dioxane
T=90 - 92°C; Mannich reaction; 60 h;
参考文献
Chukhadzhyan; Gevorkyan; Shakhatuni
Russian Journal of Organic Chemistry, 2000 , vol. 36, # 9 p. 1263 - 1264
反应条件
copper(l) chloride
T=80°C; 6 h; Inert atmosphereNeat (no solvent);
参考文献
Shaibakova; Titova; Ibragimov; Dzhemilev
Russian Journal of Organic Chemistry, 2011 , vol. 47, # 2 p. 161 - 167
参考文献
Biel et al.
Journal of the American Chemical Society, 1957 , vol. 79, p. 6184,6185
