1: 40 percent / butyllithium / tetrahydrofuran; hexane / -15 - -10 °C 2: 79 percent / Raney nickel / cyclohexane / 2 h / Heating View Scheme

<b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '1209227', constants.ctx, '0')">n-butyllithium</a>&nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '102391', constants.ctx, '0')">tetrahydrofuran</a>;&nbsp;<a href="#" onclick="return RXDsubstances(event, this, '1730733', constants.ctx, '0')">hexane</a> <br />T=-15 - -10&deg;C;&nbsp;<br /> &nbsp;

<b>Multi-step reaction with 2 steps<br /> </b>1: 79 percent / buthyllithium / tetrahydrofuran; hexane / -45 - -10 &deg;C<br />2: 50 percent / butyllithium / tetrahydrofuran; hexane / -15 - -10 &deg;C<br /> <br /> &nbsp;