3,4,5-三甲氧基苯甲酰氯合成路线 （共 203 条）
反应条件
thionyl chloride in dichloromethane Heating;
参考文献
Ghinet, Alina; Rigo, Benoit; Henichart, Jean-Pierre; Le Broc-Ryckewaert, Delphine; Pommery, Jean; Pommery, Nicole; Thuru, Xavier; Quesnel, Bruno; Gautret, Philippe
Bioorganic and Medicinal Chemistry, 2011 , vol. 19, # 20 p. 6042 - 6054
反应条件
1: 2M aq. NaOH / various solvent(s) / 0.25 h 2: thionyl chloride / 2 h / Heating View Scheme
参考文献
Takahashi, Rintaro; Nunokawa, Tatsuya; Shibuya, Tadahiro; Tomita, Ryohei; Tatewaki, Yoko; Okada, Shuji; Kimura, Tatsumi; Shimada, Satoru; Matsuda, Hiro
Bulletin of the Chemical Society of Japan, 2012 , vol. 85, # 2 p. 236 - 244
反应条件
1: Bu4NHSO4, K2CO3 / toluene / 6 h / Heating 2: 2M aq. NaOH / various solvent(s) / 0.25 h 3: thionyl chloride / 2 h / Heating View Scheme
参考文献
Sawyer, David A.; Beams, Richard M.; Blackwell, Geoffrey, J.; Brockwell, Michael A.; Cheesman, Neil J.; et al.
Journal of Medicinal Chemistry, 1995 , vol. 38, # 12 p. 2130 - 2137
参考文献
Perkin; Weizmann
Journal of the Chemical Society, 1906 , vol. 89, p. 1655
参考文献
v. Kostanecki; Tambor
Chemische Berichte, 1906 , vol. 39, p. 4023
参考文献
Graebe; Suter
Justus Liebigs Annalen der Chemie, 1905 , vol. 340, p. 230
反应条件
4-pyrrolidin-1-ylpyridine; triethylamine in dichloromethane 2.5 h; Ambient temperature;
参考文献
Walsh; Wang; Bagan; Wislocki; Miwa
Journal of Medicinal Chemistry, 1987 , vol. 30, # 1 p. 150 - 156
反应条件
1: ethanol; diethyl ether / und Erhitzen des Reaktionsprodukts mit Essigsaeure und wss.H2SO4 2: ethanol; hydrochloric acid View Scheme
参考文献
Haggett; Archer
Journal of the American Chemical Society, 1949 , vol. 71, p. 2255
反应条件
triethylamine in benzene 6 h; Heating;
参考文献
Kaminka, M. E.; Vorob'eva, V. Ya.; Nikitin, V. B.; Mikhlina, E. E.; Zhirnikova, M. L.; Yakhontov, L. N.
Pharmaceutical Chemistry Journal, 1987 , vol. 21, # 8 p. 568 - 570
Khimiko-Farmatsevticheskii Zhurnal, 1987 , vol. 21, # 8 p. 945 - 948
反应条件
hydrogenchloride in tetrahydrofuran; water 2 h; Ambient temperaturepH 2 to 3.5;
参考文献
Carceller; Almansa; Merlos; Giral; Bartroli; Garcia-Rafanell; Forn
Journal of Medicinal Chemistry, 1992 , vol. 35, # 22 p. 4118 - 4134
