3,4,5-三甲氧基苯甲酰氯合成路线 （共 203 条）
参考文献
Spaeth
Monatshefte fuer Chemie, 1919 , vol. 40, p. 138
Monatshefte fuer Chemie, 1921 , vol. 42, p. 263
反应条件
1: methanol With sodium 2: 3,4,5-trimethoxy-benzoic acid chloride in methanol T=20°C; 5 h;
参考文献
Journal of Medicinal Chemistry, , vol. 49, # 25 p. 7540 - 7544
反应条件
1.1: pyridine / CH2Cl2 / 20 h 2.1: Na2HPO4 / acetonitrile / 20 °C 2.2: 95 percent / aq. NaHCO3 / 18 h View Scheme
参考文献
Tetrahedron, , vol. 56, # 51 p. 9875 - 9883
反应条件
in potassium hydrogencarbonate; benzene
参考文献
Marion Laboratories, Inc.
Patent: US4022900 A1, 1977 ;
反应条件
triethylamine in tetrahydrofuran T=20°C; 36 h;
参考文献
Recabarren-Gajardo; Gacitaa; Murueva; Romero; Espinosa-Bustos; Mella-Raipan; Del Valle; Pessoa-Mahana; Tapia
Journal of Physical Organic Chemistry, 2011 , vol. 24, # 12 p. 1179 - 1187
反应条件
copper(l) chloride; manganese (II) chloride 1.) THF, -35 deg C, then r.t., 30 min; 2.) THF, 0 deg C; 3.) THF, -10 deg C, then r.t., 1 h; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Kiefl; Mannschreck
Synthesis, 1995 , # 8 p. 1033 - 1037
反应条件
diiodomethane; 2,2'-azo-bisisobutyronitrile; Fonderma in toluene 0.583333 h; Heating; Yield given;
参考文献
Barton, Derek H.R.; Lacher, Brigitte; Zard, Samir Z.
Tetrahedron, 1987 , vol. 43, # 19 p. 4321 - 4328
反应条件
2,2'-azo-bisisobutyronitrile; trichloromonobromomethane; Fonderma T=100°C; 0.0833333 h; Heating; Yield given. Yields of byproduct given;
参考文献
Barton, Derek H.R.; Lacher, Brigitte; Zard, Samir Z.
Tetrahedron, 1987 , vol. 43, # 19 p. 4321 - 4328
反应条件
ammonium acetate in acetone T=20°C; 48 h;
参考文献
Bioorganic and Medicinal Chemistry, , vol. 13, # 4 p. 1409 - 1413
反应条件
sodium carbonate in ethanol; water; acetone
参考文献
US5977139 A1, ;
US 5977139 A
