1: diethyl ether / 20 °C 2: oxalyl chloride; DMSO; triethylamine / CH2Cl2 / 20 °C View Scheme
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4 A molecular sieve; iodine in toluene Ambient temperature;
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1: With piperidine; pyridine Knoevenagel-Doebner reaction; Reflux; 2: With hydrogenchloride in water Cooling with ice; optical yield given as percent de;
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