2-氨基-4-甲基噻吩-3-甲腈合成路线 （共 8 条）
参考文献
Ashok; Satish Goud; Shravani; Rajaiah; Sarasija; Bhaskar
Indian Journal of Heterocyclic Chemistry, 2010 , vol. 20, # 2 p. 101 - 104
反应条件
acetonitrile T=100°C; 15 h; Sealed tube;
参考文献
Roecker, Anthony J.; Mercer, Swati P.; Harrell, C. Meacham; Garson, Susan L.; Fox, Steven V.; Gotter, Anthony L.; Prueksaritanont, Thomayant; Cabalu, Tamara D.; Cui, Donghui; Lemaire, Wei; Winrow, Christopher J.; Renger, John J.; Coleman, Paul J.
Bioorganic and Medicinal Chemistry Letters, 2014 , vol. 24, # 9 p. 2079 - 2085
反应条件
formic acid 6 h; Reflux;
参考文献
Ashok; Satish Goud; Shravani; Rajaiah; Sarasija; Bhaskar
Indian Journal of Heterocyclic Chemistry, 2010 , vol. 20, # 2 p. 101 - 104
反应条件
(i) /BRN= 605384/, (ii) NH3, (iii) NaOMe; Multistep reaction;
参考文献
Taylor,E.C.; Berger,J.G.
Journal of Organic Chemistry, 1967 , vol. 32, p. 2376 - 2378
反应条件
octasulfur; bovine serum albumin in N,N-dimethyl-formamide
T=50°C; Gewald Aminoheterocycles Synthesis; 4 h;
参考文献
Zhao, Dan-Dan; Li, Li; Xu, Fan; Wu, Qi; Lin, Xian-Fu
Journal of Molecular Catalysis B: Enzymatic, 2013 , vol. 95, p. 29 - 35
反应条件
1: in water
Gewald Aminoheterocycles Synthesis; 0.333333 h; SonicationGreen chemistry;
2: With Na2S6 in water
Gewald Aminoheterocycles Synthesis; 0.5 h; SonicationGreen chemistry;
参考文献
Liang, Chengyuan; Lei, Dong; Wang, Xiuzhen; Zhang, Qingqing; Yao, Qizheng
Journal of Sulfur Chemistry, 2013 , vol. 34, # 5 p. 458 - 463
反应条件
in ethanol; dichloromethane
参考文献
DOWELANCO
Patent: EP452002 A2, 1991 ;
反应条件
1: 170 - 180 °C / fusing
2: 1.) NO-bis(trimethylsilyl)acetamide, 2.) SnCl4, 3.) NH3-MeOH
View Scheme
参考文献
Patil, Vemanna D.; Wise, Dean S.; Townsend, Leroy B.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1980 , p. 1853 - 1858
