2-(2-噻吩基羰基)苯甲酸合成路线 （共 9 条）
反应条件
1: With sodium tetrahydroborate; sodium hydrogencarbonate in water T=20°C; Heating; 2: With hydrogenchloride in water T=20°C; pH=2; 2 h;
参考文献
Zhang, Xiaotao; Meng, Qing; He, Yudong; Wang, Chengliang; Dong, Huanli; Hu, Wenping
Science China Chemistry, 2011 , vol. 54, # 4 p. 631 - 635
反应条件
aluminium trichloride in 1,2-dichloro-ethane
Ambient temperature;
参考文献
Tedjamulia, Marvin L.; Tominaga, Yoshinori; Castle, Raymond N.; Lee, Milton L.
Journal of Heterocyclic Chemistry, 1983 , vol. 20, p. 1143 - 1148
反应条件
aluminium trichloride in thiophene; dichloromethane
参考文献
Takeda Chemical Industries, Ltd.
Patent: US5585385 A1, 1996 ;
反应条件
1: 2-Bromobenzoic acid With n-butyllithium in tetrahydrofuran
T=-78°C; 0.5 h;
2: 2-thiophenyl carboxylic ester in tetrahydrofuran
T=-78°C;
参考文献
Lim, Chae Jo; Lee, Ka Eun; Lee, Byung Ho; Oh, Kwang-Seok; Yi, Kyu Yang
Bulletin of the Korean Chemical Society, 2012 , vol. 33, # 7 p. 2389 - 2392
参考文献
Acosta, A.; Cruz, P. de la; Miguel, P. De; Diez-Barra, E.; Hoz, A. de la; et al.
Tetrahedron Letters, 1995 , vol. 36, # 12 p. 2165 - 2168
反应条件
copper(l) iodide
1.) ether, -10 deg C, 2.) ether, -5 deg C, 2.5 h; Yield given. Multistep reaction;
参考文献
Rahman, Mohammed T.; Nahar, Syeda K.
Journal of Organometallic Chemistry, 1992 , vol. 425, # 1-2 p. 201 - 208
参考文献
Steinkopf
Justus Liebigs Annalen der Chemie, 1915 , vol. 407, p. 106
反应条件
Montmorillonite K10 (free of quarz and feldspar) in neat (no solvent)
0.0583333 h; Irradiationmicrowave oven;
参考文献
Acosta, A.; Cruz, P. de la; Miguel, P. De; Diez-Barra, E.; Hoz, A. de la; et al.
Tetrahedron Letters, 1995 , vol. 36, # 12 p. 2165 - 2168
反应条件
ammonium hydroxide; zinc
Heating;
参考文献
Tedjamulia, Marvin L.; Tominaga, Yoshinori; Castle, Raymond N.; Lee, Milton L.
Journal of Heterocyclic Chemistry, 1983 , vol. 20, p. 1143 - 1148
