1: N-methylcyanamide With sodium in ethanol T=20°C; Inert atmosphere; 2: 2-chloro-acetamide in acetonitrile T=70°C; Inert atmosphere;
参考文献
Liu, Xianjun; Wang, Xihong; Li, Qigui; Kozar, Michael P.; Melendez, Victor; O Neil, Michael T.; Lin, Ai J.
Journal of Medicinal Chemistry, 2011 , vol. 54, # 13 p. 4523 - 4535