2-异亚丙基双环[2.2.1]庚烷合成路线 （共 14 条）
反应条件
methylmagnesium bromide; palladium-carbon catalyst in tetrahydrofuran
参考文献
Idemitsu Kosan Co., Ltd.
Patent: US5126065 A1, 1992 ;
反应条件
BF3*AcOH in dichloromethane
T=0°C; 0.25 h;
参考文献
Fleming, Ian; Patel, Shailesh K.; Urch, Christopher J.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1989 , p. 115 - 124
反应条件
1: 99 percent / H2 / 10percent Pd on C / diethyl ether / 2 h
2: 95 percent / diethyl ether / 2 h / -78 °C
3: 76 percent / BF3*2AcOH / CH2Cl2 / 0.25 h / 0 °C
View Scheme
参考文献
Fleming, Ian; Patel, Shailesh K.; Urch, Christopher J.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1989 , p. 115 - 124
反应条件
1: H2 / PtO2 / methanol
2: diethyl ether
3: aq. H2SO4
View Scheme
参考文献
Greene,F.D. et al.
Journal of Organic Chemistry, 1963 , vol. 28, p. 55 - 64
反应条件
potassium hydrogensulfate
T=180°C; P=90 Torr;
参考文献
McManus, Samuel P.; Ortiz, Margarita; Abramovitch, Rudolph A.
Journal of Organic Chemistry, 1981 , vol. 46, # 2 p. 336 - 342
反应条件
potassium hydrogensulfate
T=150 - 160°C; 4 h;
参考文献
McManus, Samuel P.; Ortiz, Margarita; Abramovitch, Rudolph A.
Journal of Organic Chemistry, 1981 , vol. 46, # 2 p. 336 - 342
反应条件
1: 85 percent / ZnBr2 / 1 h at O deg C, then 1 h at room temp.
2: 99 percent / H2 / 10percent Pd on C / diethyl ether / 2 h
3: 95 percent / diethyl ether / 2 h / -78 °C
4: 76 percent / BF3*2AcOH / CH2Cl2 / 0.25 h / 0 °C
View Scheme
参考文献
Fleming, Ian; Patel, Shailesh K.; Urch, Christopher J.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1989 , p. 115 - 124
反应条件
1: 95 percent / diethyl ether / 2 h / -78 °C
2: 76 percent / BF3*2AcOH / CH2Cl2 / 0.25 h / 0 °C
View Scheme
参考文献
Fleming, Ian; Patel, Shailesh K.; Urch, Christopher J.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1989 , p. 115 - 124
反应条件
1: diethyl ether
2: aq. H2SO4
View Scheme
参考文献
Greene,F.D. et al.
Journal of Organic Chemistry, 1963 , vol. 28, p. 55 - 64
反应条件
1: 76.4 percent
2: potassium bisulfate / 180 °C / 90 Torr
View Scheme
参考文献
McManus, Samuel P.; Ortiz, Margarita; Abramovitch, Rudolph A.
Journal of Organic Chemistry, 1981 , vol. 46, # 2 p. 336 - 342
