1-((4-甲基苯基)磺酰)哌啶合成路线 （共 60 条）
反应条件
triphenylphosphine in dichloromethane
T=0°C; 1 h;
参考文献
Chakravarti, Rajashree; Mano, Ajayan; Iwai, Hideo; Aldeyab, Salem S.; Kumar, R. Pradeep; Kantam, M. Lakshmi; Vinu, Ajayan
Chemistry - A European Journal, 2011 , vol. 17, # 24 p. 6673 - 6682
反应条件
N,N'-dithio-bis-piperidine in dichloromethane
Heating;
参考文献
Furukawa, Mitsuru; Sato, Kimitoshi; Okawara, Tadashi
Chemistry Letters, 1982 , p. 2007 - 2010
反应条件
1: N-ethyl-N,N-diisopropylamine / dichloromethane / 0 °C / Inert atmosphere
2: N-ethyl-N,N-diisopropylamine / dichloromethane / 2 h / 20 °C
View Scheme
参考文献
Palakurthy, Nani Babu; Mandal, Bhubaneswar
Tetrahedron Letters, 2011 , vol. 52, # 52 p. 7132 - 7134
反应条件
in dimethyl sulfoxide
T=50°C;
参考文献
Martino, Alessandro Di; Galli, Carlo; Gargano, Patrizia; Mandolini, Luigi
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1985 , p. 1345 - 1350
反应条件
1.1: SO2 / tetrahydrofuran / 1.25 h / -78 - 20 °C
1.2: 93 percent / Et3N / tetrahydrofuran / 10 h / 20 °C
2.1: 100 percent / tetrahydrofuran / 20 h / 20 °C
View Scheme
参考文献
Katritzky, Alan R.; Rodriguez-Garcia, Valerie; Nair, Satheesh K.
Journal of Organic Chemistry, 2004 , vol. 69, # 6 p. 1849 - 1852
反应条件
NiI2; 2-(2-Pyridyl)imidazoline; lithium methanolate; 4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl-4',4',5',5'-tetramethyl-1,3,2-dioxaborolane in 1-methyl-pyrrolidin-2-one
T=40°C; 16 h; Overall yield = 40 percent;
参考文献
Xu, Hailiang; Zhao, Chenglong; Qian, Qun; Deng, Wei; Gong, Hegui
Chemical Science, 2013 , vol. 4, # 10 p. 4022 - 4029
反应条件
in dichloromethane
0.5 h; Ambient temperature;
参考文献
Nishikawa; Inaba; Furukawa
Chemical and Pharmaceutical Bulletin, 1983 , vol. 31, # 4 p. 1374 - 1377
反应条件
1.1: pyridine / CH2Cl2 / -20 - 20 °C
2.1: CH2Cl2 / 48 h / Heating
3.1: NaH / dimethylformamide / 0.5 h / 20 °C
3.2: 79 percent / dimethylformamide / 1 h / 20 °C
View Scheme
参考文献
Yamanaka, Hiroyuki; Yamane, Yoshinobu; Mukaiyama, Teruaki
Heterocycles, 2004 , vol. 63, # 12 p. 2813 - 2826
反应条件
1.1: CH2Cl2 / 48 h / Heating
2.1: NaH / dimethylformamide / 0.5 h / 20 °C
2.2: 79 percent / dimethylformamide / 1 h / 20 °C
View Scheme
参考文献
Yamanaka, Hiroyuki; Yamane, Yoshinobu; Mukaiyama, Teruaki
Heterocycles, 2004 , vol. 63, # 12 p. 2813 - 2826
反应条件
1: dihydrogen peroxide; trichlorophosphate / water; acetonitrile / 25 °C
2: Amberlite IRA-400 OH(1-)-form / water; acetonitrile / 0.03 h / 25 °C
View Scheme
参考文献
Bahrami, Kiumars; Khodaei, Mohammad M.; Abbasi, Jamshid
Tetrahedron, 2012 , vol. 68, # 25 p. 5095 - 5101
