螺[5.6]十二烷-7-酮合成路线 （共 18 条）
反应条件
sodium hydride in tetrahydrofuran
10 h; Reflux;
参考文献
Venkatesha, Manjunatha Achanna; Suresh, HariPrasad
Letters in Organic Chemistry, 2013 , vol. 10, # 6 p. 457 - 461
反应条件
1: With potassium tert-butylate in tetrahydrofuran
T=20°C;
2: With ammonium chloride in tetrahydrofuran; diethyl ether; water
参考文献
ABBOTT LABORATORIES
Patent: US2009/233904 A1, 2009 ;
Location in patent: Page/Page column 80 ;
US 20090233904 A1
反应条件
ethyldiphenylorthoformate; tin(IV) chloride in dichloromethane
T=0 - 20°C;
参考文献
Kita, Yasuyuki; Yoshida, Yutaka; Mihara, Sachiko; Furukawa, Akihiro; Higuchi, Kazuhiro; Fang, Dai-Fei; Fujioka, Hiromichi
Tetrahedron, 1998 , vol. 54, # 49 p. 14689 - 14704
反应条件
thallium ethylate in chloroform
T=20°C; 24 h;
参考文献
Laboureur, J. L.; Krief, A.
Tetrahedron Letters, 1984 , vol. 25, # 25 p. 2713 - 2716
反应条件
tin(IV) chloride; trimethyl orthoformate in dichloromethane
T=0 - 20°C;
参考文献
Kita, Yasuyuki; Yoshida, Yutaka; Mihara, Sachiko; Furukawa, Akihiro; Higuchi, Kazuhiro; Fang, Dai-Fei; Fujioka, Hiromichi
Tetrahedron, 1998 , vol. 54, # 49 p. 14689 - 14704
反应条件
antimony(V) pentachloride in dichloromethane
T=15 - 20°C;
参考文献
Harada, Tsunehiro; Mukaiyama, Teruaki
Chemistry Letters, 1992 , # 1 p. 81 - 84
反应条件
chlorosulphonyl isocyanate in benzene
1.) 0 deg C, 2.) reflux, 0.5 h;
参考文献
Joseph, Sajan P.; Dhar, D. N.
Synthetic Communications, 1988 , vol. 18, # 18 p. 2295 - 2302
反应条件
1: 44.1 percent Chromat. / Al
2: 89.4 percent Chromat. / MgSO4, BF3*Et2O / CH2Cl2 / 1 h
View Scheme
参考文献
Sands
Journal of Organic Chemistry, 1994 , vol. 59, # 2 p. 468 - 471
反应条件
1: 28.9 percent Chromat. / Al
2: 89.4 percent Chromat. / MgSO4, BF3*Et2O / CH2Cl2 / 1 h
View Scheme
参考文献
Sands
Journal of Organic Chemistry, 1994 , vol. 59, # 2 p. 468 - 471
反应条件
boron trifluoride diethyl etherate; magnesium sulfate in dichloromethane
1 h; Title compound not separated from byproducts;
参考文献
Sands
Journal of Organic Chemistry, 1994 , vol. 59, # 2 p. 468 - 471
