1: (+)-artemisin With β-D-galactose in ethanol T=20 - 23°C; 1.58333 h; 2: 3-oxo-8α-hydroxy-6,11β,7αH-eudesm-4-en-6,12-olide With (chloromethyl)dimethylsilane in ethanol 2 h; Acidic conditions;

1: 56 percent / 5percent HCl / dimethylformamide / 4 h / 90 °C 2: Zn dust, acetic acid / methanol / 0.25 h / Heating 3: diethyl ether / Ambient temperature 4: 95 percent / CrO3, pyridine / CH2Cl2 / 6 h / 0 °C 5: 84 percent / LiAlH(OtBu)3 / tetrahydrofuran / 3 h / 0 °C 6: 99 percent / CSA / benzene / 0.5 h / Heating 7: 49 percent / LDA, HMPA / hexane; tetrahydrofuran / -78 - -40 °C 8: 33 percent / 30percent H2O2, acetic acid / H2O; tetrahydrofuran View Scheme