2,2’-二甲氧基联苯合成路线 （共 133 条）
反应条件
copper(II) nitrate in tetrahydrofuran T=23°C; Decomposition; coupling; 4 h;
参考文献
Harada, Genta; Yoshida, Masato; Iyoda, Masahiko
Chemistry Letters, 2000 , # 2 p. 160 - 161
反应条件
copper in acetonitrile T=20°C; 18 h;
参考文献
Cepanec, Ivica; Litvic, Mladen; Udikovic, Josipa; Pogorelic, Ivan; Lovric, Marija
Tetrahedron, 2007 , vol. 63, # 25 p. 5614 - 5621
反应条件
Me4-DACH; magnesium; cobalt(II) chloride in tetrahydrofuran T=0°C; Inert atmosphere;
参考文献
Czaplik, Waldemar Maximilian; Mayer, Matthias; Jacobi Von Wangelin, Axel
Synlett, 2009 , # 18 p. 2931 - 2934
反应条件
tris-(dibenzylideneacetone)dipalladium(0); tetrabutyl ammonium fluoride; water in tetrahydrofuran; toluene T=100°C; 2 h; Inert atmosphere;
参考文献
Pitteloud, Jean-Philippe; Zhang, Zun-Ting; Liang, Yong; Cabrera, Laura; Wnuk, Stanislaw F.
Journal of Organic Chemistry, 2010 , vol. 75, # 23 p. 8199 - 8212
反应条件
potassium phosphate; trans-[Ni(Naph)Cl(PPh3)2]; tri-cyclo-hexyl-phosphine in tetrahydrofuran T=25°C; Suzuki coupling; 48 h; Inert atmosphere;
参考文献
Leowanawat, Pawaret; Zhang, Na; Safi, Mehtap; Hoffman, David J.; Fryberger, Miriam C.; George, Aiswaria; Percec, Virgil
Journal of Organic Chemistry, 2012 , vol. 77, # 6 p. 2885 - 2892
反应条件
dichloro bis(acetonitrile) palladium(II); triphenyl-arsane; silver(l) oxide in tetrahydrofuran T=65°C; Suzuki Coupling; 24 h; Inert atmosphere; regioselective reaction;
参考文献
Pereira, Ulisses A.; Barbosa, Luiz C.A.; Maltha, Celia R.A.; Demuner, Antonio J.; Masood, Mohammed A.; Pimenta, Andrea L.
European Journal of Medicinal Chemistry, 2014 , vol. 82, p. 127 - 138
反应条件
NaH-t-AmONa-Ni(OAc)2-bpy-KI in tetrahydrofuran; benzene T=63°C; 2 h; Yields of byproduct given;
参考文献
Lourak, Mouhsine; Vanderesse, Regis; Fort, Yves; Caubere, Paul
Journal of Organic Chemistry, 1989 , vol. 54, # 20 p. 4844 - 4848
反应条件
1: With n-butyllithium in tetrahydrofuran; diethyl ether; hexane T=0°C; Substitution; Dimerization; 0.5 h; 2: With [VO(OEt)Cl2] in tetrahydrofuran; diethyl ether; hexane T=20°C; Oxidation; Alkylation; 10 h; Further stages.;
参考文献
Hirao, Toshikazu; Takada, Takashi; Ogawa, Akiya
Journal of Organic Chemistry, 2000 , vol. 65, # 5 p. 1511 - 1515
反应条件
1: methoxybenzene With 2,2,6,6-tetramethyl-piperidine; n-butyllithium; cobalt(II) dibromide in tetrahydrofuran; hexane T=0 - 20°C; 0.5 h; 2: benzophenone in tetrahydrofuran; hexane T=20°C; 3: With water in tetrahydrofuran; hexane
参考文献
Dayaker, Gandrath; Chevallier, Floris; Gros, Philippe C.; Mongin, Florence
Tetrahedron, 2010 , vol. 66, # 46 p. 8904 - 8910
反应条件
potassium tetrachloropalladate; sodium acetate in neat (no solvent) T=80°C; 4 h; Inert atmosphereGreen chemistry; regioselective reaction;
参考文献
Bej, Ansuman; Chakraborty, Amarnath; Sarkar, Amitabha
RSC Advances, 2013 , vol. 3, # 36 p. 15812 - 15819
