反应条件
1: 85 percent / H2, ethylenediamine / P-2 Ni / ethanol 2: 1) 6M NaOH, 2) 2M HCl / 1) EtOH 3: 75 percent / neat (no solvent) / 0.25 h / 170 °C 4: 1) 1-chloro-N,N,2-trimethyl-1-propenylamine, 2) NEt3 / 1) CH2Cl2, 22 deg C, 2) 22 deg C 5: 2) H2O / 1) ether, RT 6: 72 percent / NaOH / ethanol / 30 h / 22 °C View Scheme
参考文献
Bergman; Nilsson; Wickberg
Tetrahedron Letters, 1990 , vol. 31, # 19 p. 2783 - 2786
