反应条件
1: 74 percent / NH3 / ethanol / 8 h / Heating
2: 90 percent / Na2S2O4, H2O
3: 76 percent / molecular sieves / tetrahydrofuran / 2 h / Heating; molecular sieves
4: 76 percent / polyphosphate ester (PPE) / 1 h / 110 - 150 °C
5: 1.) n-butyllithium / 1.) THF, hexane, -78 deg C, 1 h, 2.) THf, hexane, room temp., 24 h
6: 1.) n-butyllithium, 2.) CuI / 1.) THF, hexane, -78 deg C, 1 h, 2.) THF, hexane, room temp., a) 1.5 h, b) 45-50 deg C, 18 h
7: 1.) ZnCl2, 4 N HCl, 2.) Na2CO3, O2 / 1.) ethanol, reflux, 96 h, 2.) room temp., 5 h
View Scheme
参考文献
Hegedus, Louis S.; Odle, Roy R.; Winton, Peter M.; Weider, Paul R.
Journal of Organic Chemistry, 1982 , vol. 47, # 13 p. 2607 - 2613
