1: benzyl alcohol With sodium hydride in N,N-dimethyl-formamide; mineral oil T=5°C; 0.25 h; 2: 4-chloro pyridine hydrochloride in N,N-dimethyl-formamide; mineral oil T=5 - 60°C;
参考文献
BOEHRINGER INGELHEIM INTERNATIONAL GMBH
Patent: US2011/275627 A1, 2011 ;
Location in patent: Page/Page column 60 ;
potassium hydroxide in isopropyl alcohol T=50°C; Rate constant;
参考文献
Rajasekar, N.; Srinivasan, V. S.; Venkatasubramanian, N.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1982 , vol. 21, # 8 p. 800 - 802