反应条件
10 percent human plasma in acetonitrile T=37°C; phosphate buffer (pH 7.4); or in undiluted plasma, or in human blood, or in aq. buffer solutions (pH 1-11) and KCl at 50 deg C; Rate constantProduct distribution;
参考文献
Nielsen; Bundgaard
Journal of Medicinal Chemistry, 1989 , vol. 32, # 3 p. 727 - 734