1: pyridine-3-aldehyde With sodium tetrahydroborate in methanol 2: With thionyl chloride in methanol 3: phosphonic acid diethyl ester With sodium hydride in tetrahydrofuran; methanol; mineral oil
参考文献
BAYLOR COLLEGE OF MEDICINE; SONG, Yongcheng
Patent: WO2013/158846 A1, 2013 ;
Location in patent: Paragraph 0179 ;