1: With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; diethylamine in N,N-dimethyl-formamide
T=20°C; Sonogashira coupling; Inert atmosphere;
2: With sodium hydroxide in N,N-dimethyl-formamide
T=140°C;
3: With palladium 10 on activated carbon in N,N-dimethyl-formamide
T=140°C;
参考文献
Sanz, Roberto; Guilarte, Veronica; Perez, Antonio
Tetrahedron Letters, 2009 , vol. 50, # 31 p. 4423 - 4426
1: diethyl ether / man loest das Produkt in konz. Schwefelsaeure und verduennt mit Wasser
2: tin dichloride; hydrogen chloride; glacial acetic acid
View Scheme
参考文献
Borsche
Chemische Berichte, 1909 , vol. 42, p. 608