1-氯-3-甲基-2-丁烯合成路线 （共 287 条）
参考文献
United Gas Improv.Co.
Patent: US2246545 , 1938 ;
反应条件
1: 1.) magnesium / 1.) ether, 0-5 deg C, 2.) ether, 20 deg C, 3 h
2: HgCl2, H2O / diethyl ether / 24 h / Ambient temperature
View Scheme
参考文献
Laduranty, Joelle; Barbot, Francis; Miginiac, Leone
Bulletin de la Societe Chimique de France, 1989 , # 6 p. 850 - 855
反应条件
(i) Mg, THF, (ii) /BRN= 2436668/; Multistep reaction;
参考文献
Bullivant,M.J.; Pattenden,G.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1976 , p. 249 - 256
反应条件
1: (i) Mg, THF, (ii) /BRN= 2436668/
2: aq. HCl / diethyl ether / 50 h / 25 °C
View Scheme
参考文献
Bullivant,M.J.; Pattenden,G.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1976 , p. 249 - 256
反应条件
triphenylphosphine; bis(dibenzylideneacetone)-palladium(0) in chloroform
T=25°C; P=2327.2 - 2585.7 Torr; 24 h;
参考文献
Sheffy; Godschalx; Stille
Journal of the American Chemical Society, 1984 , vol. 106, # 17 p. 4833 - 4840
反应条件
zinc(II) chloride in diethyl ether; dichloromethane
T=-78°C;
参考文献
Klein, Herbert; Erbe, Anne; Mayr, Herbert
Angewandte Chemie, 1982 , vol. 94, # 1 p. 63
反应条件
dichloro bis(acetonitrile) palladium(II); triphenylphosphine in chloroform-d1
T=65°C; 48 h;
参考文献
Sheffy; Godschalx; Stille
Journal of the American Chemical Society, 1984 , vol. 106, # 17 p. 4833 - 4840
反应条件
trichlorosilane; triethylamine; copper(l) iodide
参考文献
Kira,M.; Sato,K.; Sakurai,H.
Journal of the American Chemical Society, 1988 , vol. 110, p. 4599
反应条件
1: 30 percent / n-butyllithium, N,N,N',N'-tetramethylethylenediamine / tetrahydrofuran / -20 °C
2: 83 percent / hydroperoxide, vanadyl acetylacetonate / CH2Cl2 / 0 °C
3: ethanol; H2O / 16 h / Heating
4: toluene / Heating
5: 92 percent / methanesulfonyl chloride, triethylamine / CH2Cl2 / 0 °C
View Scheme
参考文献
Takano, Seiichi; Morimoto, Masamichi; Satoh, Shigeki; Ogasawara, Kunio
Chemistry Letters, 1984 , p. 1261 - 1262
反应条件
(i) NaOEt, (ii) /BRN= 878156/, (iii) aq. NaOH; Multistep reaction;
参考文献
Sankyo Company Limited
Patent: US4059641 A1, 1977 ;
