高哌嗪合成路线 - 魔法化学

219132-82-84-(4-甲基-1,4-二氮杂环庚烷-1-基)苯胺

参考文献

Hoeglund, Iisa P. J.; Silver, Satu; Engstroem, Mia T.; Salo, Harri; Tauber, Andrei; Kyyroenen, Hanna-Kaisa; Saarenketo, Pauli; Hoffren, Anna-Marja; Kokko, Kurt; Pohjanoksa, Katariina; Sallinen, Jukka; Savola, Juha-Matti; Wurster, Siegfried; Kallatsa, Oili A.
Journal of Medicinal Chemistry, 2006 , vol. 49, # 21 p. 6351 - 6363

505-66-8高哌嗪

223786-22-9

参考文献

Hoeglund, Iisa P. J.; Silver, Satu; Engstroem, Mia T.; Salo, Harri; Tauber, Andrei; Kyyroenen, Hanna-Kaisa; Saarenketo, Pauli; Hoffren, Anna-Marja; Kokko, Kurt; Pohjanoksa, Katariina; Sallinen, Jukka; Savola, Juha-Matti; Wurster, Siegfried; Kallatsa, Oili A.
Journal of Medicinal Chemistry, 2006 , vol. 49, # 21 p. 6351 - 6363

参考文献

Schneider, Raoul; Hosseini, Mir Wais; Planeix, Jean-Marc; De Cian, Andre; Fischer, Jean
Chemical Communications, 1998 , # 16 p. 1625 - 1626

505-66-8高哌嗪+

1120-87-24-溴吡啶

194853-82-2

参考文献

Di Malta, Alain; Garcia, Georges; Roux, Richard; Schoentjes, Bruno; Serradeil-Le Gal, Claudine; Tonnerre, Bernard; Wagnon, Jean
Patent: US2004/180878 A1, 2004 ;
Location in patent: Page/Page column 38 ;

参考文献

G. D. Searle and Co.
Patent: US5461047 A1, 1995 ;

参考文献

Yamanouchi Pharmaceutical Co., Ltd.
Patent: US4987132 A1, 1991 ;

505-66-8高哌嗪

283-47-61,5-二氮杂双环[3.2.2]壬烷

参考文献

McElvain; Bannister
Journal of the American Chemical Society, 1954 , vol. 76, p. 1126,1129

505-66-8高哌嗪+

776-74-9二苯基溴甲烷

30486-56-71-(二苯基甲基)六氢-1H-1,4-二氮杂卓

参考文献

Grelan Pharmaceutical Co. Ltd.; Laboratoires Fournier S.C.A.
Patent: US5872115 A1, 1999 ;

505-66-8高哌嗪+

90-99-3二苯氯甲烷

30486-56-71-(二苯基甲基)六氢-1H-1,4-二氮杂卓

参考文献

Burgess, Steven J.; Kelly, Jane X.; Shomloo, Shawheen; Wittlin, Sergio; Brun, Reto; Liebmann, Katherine; Peyton, David H.
Journal of Medicinal Chemistry, 2010 , vol. 53, # 17 p. 6477 - 6489

505-66-8高哌嗪+

65753-47-12-氯-3-三氟甲基吡啶

243666-15-1

参考文献

ASTRAZENECA AB; ASTRAZENECA UK LIMITED
Patent: WO2007/122411 A1, 2007 ;
Location in patent: Page/Page column 28 ;
WO 2007/122411 A1