(±)-反-1,2-环戊二醇合成路线 （共 48 条）
反应条件
N-ethyl-N,N-diisopropylamine; (9S)-6'-methoxycinchonan-9-yl diphenylphosphinite in various solvent(s)
T=-78°C; 1 h; Title compound not separated from byproducts;
参考文献
Mizuta, Shinya; Ohtsubo, Yutaka; Tsuzuki, Takeo; Fujimoto, Tetsuya; Yamamoto, Iwao
Tetrahedron Letters, 2006 , vol. 47, # 47 p. 8227 - 8229
反应条件
N-ethyl-N,N-diisopropylamine; (9S)-6'-methoxycinchonan-9-yl diphenylphosphinite in various solvent(s)
T=-78°C; 1 h; Title compound not separated from byproducts;
参考文献
Mizuta, Shinya; Ohtsubo, Yutaka; Tsuzuki, Takeo; Fujimoto, Tetsuya; Yamamoto, Iwao
Tetrahedron Letters, 2006 , vol. 47, # 47 p. 8227 - 8229
反应条件
Boc-L-(π-Me)-His-(A)Gly-L-Cha-L-Phe-OMe; diisopropyl-carbodiimide in toluene
T=0°C; Steglich esterification; 10 h; Inert atmosphere; optical yield given as percent eeenantioselective reaction;
参考文献
Hrdina, Radim; Mueller, Christian E.; Schreiner, Peter R.
Chemical Communications, 2010 , vol. 46, # 15 p. 2689 - 2690
反应条件
2,3-butanediol dehydrogenase from Bacillus subtilis in aq. buffer
T=30°C; pH=8; 4 h; Enzymatic reaction; Reagent/catalyst; enantioselective reaction;
参考文献
Zhang, Jiandong; Xu, Tingting; Li, Zhi
Advanced Synthesis and Catalysis, 2013 , vol. 355, # 16 p. 3147 - 3153
反应条件
cyclic dioldehydrogenase from Rhodococcus sp. Moj-3449 in aq. buffer
T=30°C; pH=8; 8 h; Enzymatic reaction; enantioselective reaction;
参考文献
Zhang, Jiandong; Xu, Tingting; Li, Zhi
Advanced Synthesis and Catalysis, 2013 , vol. 355, # 16 p. 3147 - 3153
反应条件
1: (+/-)-trans-cyclopentane-1,2-diol With (5aS,10bR)-9-nitro-2-phenyl-4,5a,6,10b-tetrahydroindeno[2,1-b][1,2,4]triazolo[4,3-d][1,4]oxazin-2-ium tetrafluoroborate; 4-(N,N-dimethylamino)benzoic acid; N,N,N',N'-tetra-methylnaphthalene-1,8-diamine in chloroform
T=20°C; 0.166667 h;
2: 2-bromo-3-phenylpropanal in chloroform
T=0°C; 14 h;
参考文献
Kuwano, Satoru; Harada, Shingo; Kang, Bubwoong; Oriez, Raphael; Yamaoka, Yousuke; Takasu, Kiyosei; Yamada, Ken-Ichi
Journal of the American Chemical Society, 2013 , vol. 135, # 31 p. 11485 - 11488
反应条件
C43H60N6O8; N-ethyl-N,N-diisopropylamine in toluene
T=0°C; 24 h; Inert atmosphere; enantioselective reaction;
参考文献
Hofmann, Christine; Schuler, Soeren M. M.; Wende, Raffael C.; Schreiner, Peter R.
Chemical Communications, 2014 , vol. 50, # 10 p. 1221 - 1223
反应条件
ueber das Strychnin-Salz des Disulfo-Derivats;
参考文献
Helferich; Hiltmann
Chemische Berichte, 1937 , vol. 70, p. 308,310, 312
