O-(叔丁基)-N-[苄氧羰基]-L-酪氨酸甲酯合成路线 （共 6 条）
反应条件
sulfuric acid in dichloromethane
36 h; Ambient temperature;
参考文献
Bastiaans, Harold M.M.; Van der Baan, Juul L.; Ottenheijm, Harry C.J.
Journal of Organic Chemistry, 1997 , vol. 62, # 12 p. 3880 - 3889
反应条件
1: 98 percent / Na2CO3 / CH2Cl2; H2O / 2.5 h / 0 - 20 °C
2: 89 percent / H2SO4 / CH2Cl2 / 36 h / Ambient temperature
View Scheme
参考文献
Bastiaans, Harold M.M.; Van der Baan, Juul L.; Ottenheijm, Harry C.J.
Journal of Organic Chemistry, 1997 , vol. 62, # 12 p. 3880 - 3889
反应条件
1: 100 percent / SOCl2 / 1.) room temperature, 2 h, 2.) reflux, 0.5 h
2: 98 percent / Na2CO3 / CH2Cl2; H2O / 2.5 h / 0 - 20 °C
3: 89 percent / H2SO4 / CH2Cl2 / 36 h / Ambient temperature
View Scheme
参考文献
Bastiaans, Harold M.M.; Van der Baan, Juul L.; Ottenheijm, Harry C.J.
Journal of Organic Chemistry, 1997 , vol. 62, # 12 p. 3880 - 3889
反应条件
1: 91 percent / aq. Na2CO3 / CH2Cl2; toluene / 20 °C
2: H2SO4 / CH2Cl2 / 72 h / 20 °C
View Scheme
参考文献
Caplar, Vesna; Raza, Zlata; Katalenic, Darinka; Zinic, Mladen
Croatica Chemica Acta, 2003 , vol. 76, # 1 p. 23 - 36
反应条件
1: 91 percent / aq. Na2CO3 / CH2Cl2; toluene / 20 °C
2: H2SO4 / CH2Cl2 / 72 h / 20 °C
View Scheme
参考文献
Caplar, Vesna; Raza, Zlata; Katalenic, Darinka; Zinic, Mladen
Croatica Chemica Acta, 2003 , vol. 76, # 1 p. 23 - 36
反应条件
sodium hydroxide in methanol
T=20°C;
参考文献
Caplar, Vesna; Raza, Zlata; Katalenic, Darinka; Zinic, Mladen
Croatica Chemica Acta, 2003 , vol. 76, # 1 p. 23 - 36
