N-(4-甲氧基苯基)-2-苯基乙酰胺合成路线 (共 17 条)
反应条件
1: SOCl2 / CHCl3 / 2 h / Heating
2: 90 percent / Et3N 1 eq. / benzene / 6 h / Heating
View Scheme
参考文献
Mule, A.; Pirisino, G.; Piu, L.; Satta, M.; Manca, P.; Peana, A.
Farmaco, Edizione Scientifica, 1985 , vol. 40, # 1 p. 25 - 33
反应条件
Sn[N(SiMe3)2]2
1.) THF, hexane, RT, 5 min; 2.) THF, hexane, RT, overnight; Yield given. Multistep reaction;
参考文献
Wang; Restituyo; Roskamp
Tetrahedron Letters, 1993 , vol. 34, # 45 p. 7217 - 7220
反应条件
1: 51 percent
2: 65 percent / H2SO4, NaNO2
View Scheme
参考文献
Joshi, Vidya; Jalisatgi, S. S.; Hari, M. I.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1986 , vol. 25, p. 83 - 84
参考文献
Buck; Ide
Journal of the American Chemical Society, 1931 , vol. 53, p. 1536,1541
Full Text Show Details
Jenkins
Journal of the American Chemical Society, 1933 , vol. 55, p. 703,704, 2896, 2897
反应条件
1: With phosphorus pentachloride in benzene
1 h; Heating;
2: With triethylamine in diethyl ether
6 h; Heating;
参考文献
Sung, Kuangsen; Chen, Fu-Lin; Huang, Pin-Mei; Chiang, Shu-Min
Tetrahedron, 2006 , vol. 62, # 1 p. 171 - 181
反应条件
trichlorophosphate in N,N-dimethyl-formamide
参考文献
Blackburn, Thomas P.; Cox, Barry; Guildford, Allen J.; Count, David J. Le; Middlemiss, Derek N.; et al.
Journal of Medicinal Chemistry, 1987 , vol. 30, # 12 p. 2252 - 2259
反应条件
trichlorophosphate
T=90°C; 4 h; Yield given;
参考文献
Gazit, Aviv; App, Harald; McMahon, Gerald; Chen, Jefferey; Levitzki, Alexander; Bohmer, Frank D.
Journal of Medicinal Chemistry, 1996 , vol. 39, # 11 p. 2170 - 2177