2,3-二甲基-1,3-丁二烯合成路线 （共 777 条）
反应条件
in neat (no solvent)
byproducts: N2, ClCH2CO2CH2CH3; 1 equiv of diazoester adding slowly to an equimolar mixt. of Ge and Sn deriv. to result in exothermic reaction with N2 evolution; after 4 h at 20°C concg., diene ligand adding, heating in a sealed tube for 12h at 120°C; analyzed by gas chromy. and NMR spectroscopy;
参考文献
Castel, A.; Riviere, P.; Satge, J.
Journal of Organometallic Chemistry, 1982 , vol. 232, # 2 p. 137 - 146
反应条件
1: With nitrosonium ethyl sulfate in dichloromethane
Nitrosation; pH=8 - 9;
2: With sodium carbonate in water
Hydrolysis;
参考文献
Zyk, Nikolai V.; Nesterov, Evgueni E.; Khlobystov, Andrei N.; Zefirov, Nikolai S.; Barnhurst, Loren A.; Kutateladze, Andrei G.
Journal of Organic Chemistry, 1999 , vol. 64, # 19 p. 7121 - 7128
反应条件
1,2,3-benzenetriol
T=165°C;
参考文献
Gault; Laloi
Bulletin de la Societe Chimique de France, 1952 , p. 1079
反应条件
hydroquinone in xylene
T=175°C;
参考文献
Perun,T.J. et al.
Journal of Organic Chemistry, 1963 , vol. 28, # 11 p. 2937 - 2943
反应条件
[(η6-C10H8)Rh(cod)]BF4 in dichloromethane
T=15°C; 0.25 h;
参考文献
Paik, Se-Jung; Son, Seung Uk; Chung, Young Keun
Organic Letters, 1999 , vol. 1, # 13 p. 2045 - 2047
反应条件
silver hexafluoroantimonate; RhCl[N,N'-bis(2,6-di-iPrC6H3)imidazol-2-ylidene](COD) in dichloromethane
Diels-Alder reaction; 2 h; Title compound not separated from byproducts;
参考文献
Lee, Sang Ick; Park, Se Yeoun; Park, Ji Hoon; Jung, Il Gu; Choi, Soo Young; Chung, Young Keun; Lee, Bun Yeoul
Journal of Organic Chemistry, 2006 , vol. 71, # 1 p. 91 - 96
反应条件
2: 93 percent / Na-Hg, NaH2PO4*2H2O / methanol
View Scheme
参考文献
Davis, Anthony P.; Whitham, Gordon H.
Journal of the Chemical Society, Chemical Communications, 1980 , # 13 p. 639 - 640
反应条件
acetic acid
1) 100 deg C, 2) 25 deg C, 13.5 h; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Singleton, Daniel A.; Leung, Shun-Wang
Journal of Organic Chemistry, 1992 , vol. 57, # 18 p. 4796 - 4797
反应条件
1: 2,3-dimethyl-buta-1,3-diene With HInCl2 in tetrahydrofuran
T=20°C; 5 h;
2: 2,3-butadione in tetrahydrofuran
T=20°C; 14 h; regioselective reaction;
参考文献
Hayashi, Naoki; Honda, Hiroyuki; Shibata, Ikuya; Yasuda, Makoto; Baba, Akio
Synlett, 2008 , # 9 p. 1407 - 1411
反应条件
1: hydrogen; octacarbonyl dicobalt; diethyl ether / 135 - 175 °C / 239040 - 286848 Torr
2: platinum; methylcyclohexane / Hydrogenation
View Scheme
参考文献
Adkins; Williams
Journal of Organic Chemistry, 1952 , vol. 17, p. 980,986
