sodium hydrogen sulphate; silica gel in 1,2-dichloro-ethane T=80°C; 1 h; Concentration;

1: With lithium in tetrahydrofuran T=-80 - -50°C; 1 h; 2: With methanol in tetrahydrofuran T=-80°C; Further stages.;

indium(III) chloride in 1,2-dichloro-ethane T=50°C; 1 h; Inert atmosphere;

silica gel supported sodium hydrogen sulfate in anhydrous dichloroethane T=60°C; 0.5 h;

triphenylphosphine; silver(l) oxide; bis(dibenzylideneacetone)-palladium(0) in ethylene glycol dimethyl ether T=90°C; 18 h; Glovebox; regioselective reaction;

silver tetrafluoroborate in acetonitrile 68 h;

1.1: sec.-butyllithium; N,N,N',N,-tetramethylethylenediamine / diethyl ether; cyclohexane; hexane / 4 h / -78 °C 1.2: 1.17 h 1.3: |Reflux 2.1: silver(l) oxide; triphenylphosphine; bis(dibenzylideneacetone)-palladium(0) / ethylene glycol dimethyl ether / 18 h / 90 °C / |Glovebox View Scheme

1.1: triethylamine / dichloromethane / 24 h / |Reflux; |Inert atmosphere 2.1: sec.-butyllithium; N,N,N',N,-tetramethylethylenediamine / diethyl ether; cyclohexane; hexane / 4 h / -78 °C 2.2: 1.17 h 2.3: |Reflux 3.1: silver(l) oxide; triphenylphosphine; bis(dibenzylideneacetone)-palladium(0) / ethylene glycol dimethyl ether / 18 h / 90 °C / |Glovebox View Scheme

T=165 - 170°C; 30 h;

in acetonitrile T=20°C; Yields of byproduct given;