N-亚苄基-4-甲基苯磺酰胺合成路线 （共 129 条）
反应条件
potassium carbonate in ethanol
T=20°C; 1 h; Green chemistry; Reagent/catalystTimeSolvent; chemoselective reaction;
参考文献
Li, Zheng; Li, Rongzhi; Zheng, Huanhuan; Wen, Fei; Li, Hongbo; Yin, Junjun; Yang, Jingya
Journal of the Brazilian Chemical Society, 2013 , vol. 24, # 11 p. 1739 - 1743
反应条件
trimethylsilyl cyanide; iodine in dichloromethane
T=20°C; Strecker reaction; 1 h;
参考文献
Das, Biswanath; Balasubramanyam, Penagaluri; Krishnaiah, Maddeboina; Veeranjaneyulu, Boyapati; Reddy, Gandolla Chinna
Synthesis, 2009 , # 20 p. 3467 - 3471
反应条件
1: With dimethyl sulfoxide
T=20°C; Strecker reaction; 2 h;
2: With water
参考文献
Kadam, Santosh T.; Thirupathi, Ponnaboina; Kim, Sung Soo
Synthesis, 2011 , # 6 art. no. F55810SS, p. 919 - 923
反应条件
in tetrahydrofuran; diethyl ether
T=20°C; Grignard addition; 12 h;
参考文献
Prasad, B. A. Bhanu; Bisai, Alakesh; Singh, Vinod K.
Organic Letters, 2004 , vol. 6, # 26 p. 4829 - 4831
反应条件
in tetrahydrofuran
T=0°C; 1.5 h;
参考文献
Arai, Shigeru; Koike, Yuka; Nishida, Atsushi
Advanced Synthesis and Catalysis, 2010 , vol. 352, # 5 p. 893 - 900
反应条件
1: cyclohexenon; phenyl-magnesium bromide With Taniaphos SL-T001-1; copper(l) chloride in tert-butyl methyl ether
T=-60°C; Michael condensation; 2 h; Inert atmosphere;
2: N-benzylidene-4-methylbenzenesulfonamide in 2-methyl tetrahydrofuran; tert-butyl methyl ether
T=-60 - 20°C; Mannich reaction; Inert atmosphere; optical yield given as percent eeenantioselective reaction;
参考文献
Sebesta, Radovan; Bilcik, Filip; Fodran, Peter
European Journal of Organic Chemistry, 2010 , # 29 p. 5666 - 5671
反应条件
carbon monoxide; tetrabutylammomium bromide; N-ethyl-N,N-diisopropylamine; {PdCl[CH(Tol)N(Bn)COPh]}2 in tetrahydrofuran; acetonitrile
T=65°C; P=760 Torr; 24 h; Product distribution; Further Variations:CatalystsPressuresReagentsTemperatures;
参考文献
Siamaki, Ali R.; Arndtsen, Bruce A.
Journal of the American Chemical Society, 2006 , vol. 128, # 18 p. 6050 - 6051
反应条件
1.1: n-BuLi / tetrahydrofuran; hexane / 0.08 h / -40 °C
1.2: 67 percent / tetrahydrofuran; hexane / 2 h / -40 - -20 °C
2.1: 71 percent / t-BuOK / dimethylsulfoxide / 50 °C
View Scheme
参考文献
Amombo, Marlyse Okala; Hausherr, Arndt; Reissig, Hans-Ulrich
Synlett, 1999 , # 12 p. 1871 - 1874
反应条件
1: copper (II) acetate monohydrate; C72H68N2O6 / toluene / 24 h / 20 °C
2: hydrogen; palladium on activated charcoal / methanol / 20 °C
3: magnesium / methanol / 0.83 h / |Sonication
View Scheme
参考文献
Choudhary, Manoj K.; Das, Anjan; Kureshy, Rukhsana I.; Kumar, Manish; Khan, Noor-Ul H.; Abdi, Sayed H. R.; Bajaj, Hari C.
Catalysis Science and Technology, 2014 , vol. 4, # 2 p. 548 - 555
反应条件
in dimethyl sulfoxide
13 h; Ambient temperature;
参考文献
Nadir, Upender K.; Koul, Veerinder K.
Synthesis, 1983 , # 7 p. 554
