1: 4-iodobenzoic acid ethyl ester With isopropylmagnesium chloride in tetrahydrofuran T=-40°C; 0.916667 h; 2: With lithium chloride; manganese (II) chloride in tetrahydrofuran T=-40°C; 3: 2-chlorobenzophenone in tetrahydrofuran T=0°C; 2 h;
1: phenyl-magnesium bromide With zinc(II) chloride in tetrahydrofuran T=20°C; 1 h; 2: 2-chlorobenzophenone in tetrahydrofuran 120 h; Reflux;
参考文献
Wang, Fang; Good, James A. D.; Rath, Oliver; Kaan, Hung Yi Kristal; Sutcliffe, Oliver B.; MacKay, Simon P.; Kozielski, Frank
Journal of Medicinal Chemistry, 2012 , vol. 55, # 4 p. 1511 - 1525
