1-氯-3-(2-苯基乙炔)苯合成路线 （共 14 条）
反应条件
2: (i) aq. KMnO4, (ii) /BRN= 102415/ View Scheme
参考文献
Seyferth,D. et al.
Journal of the American Chemical Society, 1975 , vol. 97, # 26 p. 7417 - 7426
反应条件
2: (i) aq. KMnO4, (ii) /BRN= 102415/ View Scheme
参考文献
Seyferth,D. et al.
Journal of the American Chemical Society, 1975 , vol. 97, # 26 p. 7417 - 7426
反应条件
N-iodo-succinimide; dimethyl sulfoxide in acetonitrile
T=100°C; 11 h;
参考文献
Chikugo, Takuya; Yauchi, Yuta; Ide, Masataka; Iwasawa, Tetsuo
Tetrahedron, 2014 , vol. 70, # 26 p. 3988 - 3993
反应条件
bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; tributyl-amine; potassium carbonate in water
T=20°C; 1 h;
参考文献
Bumagin; Sukhomlinova; Luzikova; Tolstaya; Beletskaya
Russian Journal of Organic Chemistry, 1996 , vol. 32, # 7 p. 996 - 1000
反应条件
1: iodobenzene; acetylenecarboxylic acid With bis-triphenylphosphine-palladium(II) chloride; 1,8-diazabicyclo[5.4.0]undec-7-ene; 1,4-di(diphenylphosphino)-butane in dimethyl sulfoxide
T=50°C; 4 h;
2: 1-bromo-3-chlorobenzene in dimethyl sulfoxide
T=120°C; 4 h;
参考文献
Lee, Hee Joon; Park, Kyungho; Bae, Goun; Choe, Jaehoon; Song, Kwang Ho; Lee, Sunwoo
Tetrahedron Letters, 2011 , vol. 52, # 39 p. 5064 - 5067
反应条件
[{Pd(μ-Cl){κ2-P,C-P(iPr)2(OC6H3-2-Ph)}}2]; triethylamine in water; dimethyl sulfoxide
T=40°C; Sonogashira coupling; 4 h; Inert atmosphere;
参考文献
Marziale, Alexander N.; Schlueter, Johannes; Eppinger, Joerg
Tetrahedron Letters, 2011 , vol. 52, # 48 p. 6355 - 6358
反应条件
caesium carbonate; PdCl(C6H3-2,6-(OPiPr2)); zinc(II) chloride in 1,4-dioxane
T=160°C; 24 h;
参考文献
Eberhard, Michael R.; Wang, Zhaohui; Jensen, Craig M.
Chemical Communications, 2002 , # 8 p. 818 - 819
反应条件
tris(dibenzylideneacetone)dipalladium (0); tri-tert-butyl phosphine; tetrabutyl ammonium fluoride in tetrahydrofuran; 1-methyl-pyrrolidin-2-one
T=90°C; 12 h;
参考文献
Moon, Jeongju; Jang, Mihee; Lee, Sunwoo
Journal of Organic Chemistry, 2009 , vol. 74, # 3 p. 1403 - 1406
反应条件
CuI(xantphos); caesium carbonate in N,N-dimethyl-formamide
T=135°C; Sonogashira type reaction; 0.166667 h; Inert atmosphereMicrowave irradiation;
参考文献
Tsai, Wen-Ting; Lin, Yun-Yung; Wang, Yu-Jen; Lee, Chin-Fa
Synthesis, 2012 , vol. 44, # 10 p. 1507 - 1510
反应条件
piperidine; C20H26Br2N2O4Pd2 in 1-methyl-pyrrolidin-2-one
T=100°C; Sonogashira Cross-Coupling; 1 h;
参考文献
Hajipour, Abdol R.; Rahimi, Hannaneh; Rafiee, Fatemeh
Applied Organometallic Chemistry, 2012 , vol. 26, # 12 p. 727 - 730
