4-(4-乙氧苯氧基)苯胺盐酸盐合成路线 （共 5 条）
反应条件
1: hydrogen bromide / 4 h / Inert atmosphere; Reflux
2: potassium carbonate; potassium iodide / acetonitrile / Inert atmosphere; Reflux
3: stannous chloride-dihydrate; ethanol / 1 h / 70 °C / Inert atmosphere
View Scheme
参考文献
Li, Jie; Pei, Shuchen; Zhu, Yingxi; Wu, Jianbo; Chen, Yin; Zhang, Weiyu; Wu, Yong
Letters in Drug Design and Discovery, 2012 , vol. 9, # 4 p. 379 - 388
反应条件
1: potassium carbonate; potassium iodide / acetonitrile / Inert atmosphere; Reflux
2: stannous chloride-dihydrate; ethanol / 1 h / 70 °C / Inert atmosphere
View Scheme
参考文献
Li, Jie; Pei, Shuchen; Zhu, Yingxi; Wu, Jianbo; Chen, Yin; Zhang, Weiyu; Wu, Yong
Letters in Drug Design and Discovery, 2012 , vol. 9, # 4 p. 379 - 388
反应条件
stannous chloride-dihydrate; ethanol
T=70°C; 1 h; Inert atmosphere;
参考文献
Li, Jie; Pei, Shuchen; Zhu, Yingxi; Wu, Jianbo; Chen, Yin; Zhang, Weiyu; Wu, Yong
Letters in Drug Design and Discovery, 2012 , vol. 9, # 4 p. 379 - 388
反应条件
1: sodium hydride / N,N-dimethyl-formamide / 20 - 80 °C / Inert atmosphere
2: hydrogen bromide / 4 h / Inert atmosphere; Reflux
3: potassium carbonate; potassium iodide / acetonitrile / Inert atmosphere; Reflux
4: stannous chloride-dihydrate; ethanol / 1 h / 70 °C / Inert atmosphere
View Scheme
参考文献
Li, Jie; Pei, Shuchen; Zhu, Yingxi; Wu, Jianbo; Chen, Yin; Zhang, Weiyu; Wu, Yong
Letters in Drug Design and Discovery, 2012 , vol. 9, # 4 p. 379 - 388
反应条件
1: sodium hydride / N,N-dimethyl-formamide / 20 - 80 °C / Inert atmosphere
2: hydrogen bromide / 4 h / Inert atmosphere; Reflux
3: potassium carbonate; potassium iodide / acetonitrile / Inert atmosphere; Reflux
4: stannous chloride-dihydrate; ethanol / 1 h / 70 °C / Inert atmosphere
View Scheme
参考文献
Li, Jie; Pei, Shuchen; Zhu, Yingxi; Wu, Jianbo; Chen, Yin; Zhang, Weiyu; Wu, Yong
Letters in Drug Design and Discovery, 2012 , vol. 9, # 4 p. 379 - 388
