2-[(10-溴癸基)氧基]四氢-2H-吡喃合成路线 （共 50 条）
反应条件
1: 1.) n-BuLi / 1.) THF, -20 deg C 2: 1.) n-BuLi / 1.) THF, -20 deg C 3: 91 percent / Et3N, 4-dimethylaminopyridine (DMAP) / CH2Cl2 4: 84 percent / TsOH / methanol 5: DMSO, py, TFA, DCC / benzene 6: AgNO3, aq. NaOH / tetrahydrofuran 7: 53 percent / aq. NaOH / methanol 8: 47 percent / 2,4,6-Cl3C6H2COCl, Et3N, DMAP / toluene / Heating 9: 42 percent / N-bromosuccinimide (NBS), H2O / acetone View Scheme
参考文献
Spracklin; Weiler
Journal of the Chemical Society - Series Chemical Communications, 1992 , # 18 p. 1347 - 1349
反应条件
1: HMPA / tetrahydrofuran 2: p-toluenesulfonic acid / methanol 3: H2 / Pd/BaSO4 View Scheme
参考文献
Riba; Eizaguirre; Sans; Quero; Guerrero
Pesticide Science, 1994 , vol. 41, # 2 p. 97 - 103
反应条件
1: 99 percent / CrO3, H2SO4 / acetone 2: 77 percent / 10percent H2SO4 / 18 h / Heating View Scheme
参考文献
Navarro, Isabel; Mas, Esther; Fabrias, Gemma; Camps, Francisco
Bioorganic and Medicinal Chemistry, 1997 , vol. 5, # 7 p. 1267 - 1274
反应条件
1: HMPA / tetrahydrofuran 2: p-toluenesulfonic acid / methanol 3: H2 / Pd/BaSO4 4: pyridine View Scheme
参考文献
Riba; Eizaguirre; Sans; Quero; Guerrero
Pesticide Science, 1994 , vol. 41, # 2 p. 97 - 103
反应条件
1: CuCl / tetrahydrofuran / 5 h / Heating 2: p-TsOH / methanol / 8 h / Ambient temperature 3: 81 percent / HBr, H2SO4 / 4 h / Heating View Scheme
参考文献
Miyakoshi, Tetsuo; Du, Yumin; Kumanotani, Ju
Bulletin of the Chemical Society of Japan, 1991 , vol. 64, # 3 p. 1054 - 1056
反应条件
Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 851 - 860
反应条件
Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 851 - 860
反应条件
1: 1) n-BuLi / 1a) diglyme, hexane, r.t., 2 h, 1b) 50 deg C, 1 h, 2) diglyme, 110 deg C, 2 h 2: p-TsOH / methanol / 3 h / Heating 3: 95 percent / H2 / 10percent Pd-C / tetrahydrofuran / 4 h View Scheme
参考文献
Iyer, R. R.; Mamdapur, V. R.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1986 , vol. 25, p. 1216 - 1219
反应条件
1: HMPA / tetrahydrofuran 2: p-toluenesulfonic acid / methanol 3: H2 / Pd/BaSO4 4: pyridine 5: CrO3; pyridine / CH2Cl2 View Scheme
参考文献
Riba; Eizaguirre; Sans; Quero; Guerrero
Pesticide Science, 1994 , vol. 41, # 2 p. 97 - 103
反应条件
chromium(VI) oxide; sulfuric acid in acetone
参考文献
Navarro, Isabel; Mas, Esther; Fabrias, Gemma; Camps, Francisco
Bioorganic and Medicinal Chemistry, 1997 , vol. 5, # 7 p. 1267 - 1274
