2-氨基-3,5-二氢-3-[(苯基甲氧基)甲基]-4H-吡咯并[3,2-d]嘧啶-4-酮合成路线 （共 6 条）
反应条件
hydrogen; palladium dihydroxide in methanol P=2585.74 Torr; 5 h;
参考文献
Liu, Mao-Chin; Luo, Mei-Zhen; Mozdziesz, Diane E.; Sartorelli, Alan C.
Synthetic Communications, 2002 , vol. 32, # 24 p. 3797 - 3802
反应条件
ammonia in ethanol
T=165 - 170°C; 4 h;
参考文献
Liu, Mao-Chin; Luo, Mei-Zhen; Mozdziesz, Diane E.; Sartorelli, Alan C.
Synthetic Communications, 2002 , vol. 32, # 24 p. 3797 - 3802
反应条件
1: 95 percent / sodium hydrogen sulfite / tetrahydrofuran; H2O / 12 h / 20 °C
2: 95 percent / ammonia / ethanol / 4 h / 165 - 170 °C
View Scheme
参考文献
Liu, Mao-Chin; Luo, Mei-Zhen; Mozdziesz, Diane E.; Sartorelli, Alan C.
Synthetic Communications, 2002 , vol. 32, # 24 p. 3797 - 3802
反应条件
1: 90 percent / 1,8-diazabicyclo[5.4.0]undec-7-ene / dimethylformamide / 2 h / 20 °C
2: 91 percent / dimethylformamide / 40 h / 20 °C
3: 95 percent / sodium hydrogen sulfite / tetrahydrofuran; H2O / 12 h / 20 °C
4: 95 percent / ammonia / ethanol / 4 h / 165 - 170 °C
View Scheme
参考文献
Liu, Mao-Chin; Luo, Mei-Zhen; Mozdziesz, Diane E.; Sartorelli, Alan C.
Synthetic Communications, 2002 , vol. 32, # 24 p. 3797 - 3802
反应条件
1: 90 percent / 1,8-diazabicyclo[5.4.0]undec-7-ene / dimethylformamide / 2 h / 20 °C
2: 91 percent / dimethylformamide / 40 h / 20 °C
3: 95 percent / sodium hydrogen sulfite / tetrahydrofuran; H2O / 12 h / 20 °C
4: 95 percent / ammonia / ethanol / 4 h / 165 - 170 °C
View Scheme
参考文献
Liu, Mao-Chin; Luo, Mei-Zhen; Mozdziesz, Diane E.; Sartorelli, Alan C.
Synthetic Communications, 2002 , vol. 32, # 24 p. 3797 - 3802
反应条件
1: 91 percent / dimethylformamide / 40 h / 20 °C
2: 95 percent / sodium hydrogen sulfite / tetrahydrofuran; H2O / 12 h / 20 °C
3: 95 percent / ammonia / ethanol / 4 h / 165 - 170 °C
View Scheme
参考文献
Liu, Mao-Chin; Luo, Mei-Zhen; Mozdziesz, Diane E.; Sartorelli, Alan C.
Synthetic Communications, 2002 , vol. 32, # 24 p. 3797 - 3802
