1,2,3,4-四氢萘-2-甲腈合成路线 （共 14 条）
反应条件
1: 1.) n-BuLi, 2.) Et3N / 1.) diglyme, -10 - -20 deg C, 30 min, 2.) room temperature, 3 h
2: methanol; H2O / Heating
3: 1.) n-BuLi, 2.) MeSO2Cl / 1.) THF, -78 deg C, 20 min, 2.) -78 deg C, 30 min; room temperature, 2 d
4: 89 percent / t-Bu4NF / acetonitrile / 1 h / Ambient temperature
View Scheme
参考文献
Ito; Nakatsuka; Saegusa
Journal of the American Chemical Society, 1982 , vol. 104, # 26 p. 7609 - 7622
反应条件
1: methanol; H2O / Heating
2: 1.) n-BuLi, 2.) MeSO2Cl / 1.) THF, -78 deg C, 20 min, 2.) -78 deg C, 30 min; room temperature, 2 d
3: 89 percent / t-Bu4NF / acetonitrile / 1 h / Ambient temperature
View Scheme
参考文献
Ito; Nakatsuka; Saegusa
Journal of the American Chemical Society, 1982 , vol. 104, # 26 p. 7609 - 7622
反应条件
4-methoxy-toluene in acetonitrile
Irradiation; Further byproducts given;
参考文献
Albini, Angelo; Spreti, Silvia
Tetrahedron, 1984 , vol. 40, # 15 p. 2975 - 2982
反应条件
(Et2N)3S(1+)*TMSF2(1-); TMS-SnBu3 in N,N-dimethyl-formamide
参考文献
Sato, Hiroki; Isono, Naohiro; Miyoshi, Irie; Mori, Miwako
Tetrahedron, 1996 , vol. 52, # 24 p. 8143 - 8158
