L-半胱氨酸盐酸盐无水物合成路线 （共 109 条）
反应条件
water; potassium acetate
参考文献
GLENMARK PHARMACEUTICALS LTD.
Patent: WO2005/58849 A1, 2005 ;
Location in patent: Page/Page column 40 ;
WO 2005/058849 A1
参考文献
Gabriel
Chemische Berichte, 1905 , vol. 38, p. 637
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Moerner
Hoppe-Seyler's Zeitschrift fuer Physiologische Chemie, 1904 , vol. 42, p. 354
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Friedmann; Baer
B.Ph.P., 1906 , vol. 8, p. 326
反应条件
copper(I) oxide; sulfuric acid anschliessendes Erwaermen mit einer wss. Loesung von 4-Chlor-benzoldiazonium-sulfat;
参考文献
West; Mathura; Black
Journal of Biological Chemistry, 1951 , vol. 193, p. 133
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Parke; Williams
Biochemical Journal, 1951 , vol. 48, p. 624,625
参考文献
ZAMBON GROUP S.p.A.
Patent: EP1053225 B1, 2004 ;
Location in patent: Page 5-6 ;
反应条件
copper(I) oxide; sulfuric acid anschliessend Behandeln mit wss. 3-Trifluormethyl-benzoldiazonium-sulfat-Loesung;
参考文献
Goodman et al.
Journal of Organic Chemistry, 1958 , vol. 23, p. 1251,1956
反应条件
sodium hydroxide in ethanol
参考文献
ZHU, YIZHUN; Wang, Qian; Zhu, Yichun; Mu, Qing
Patent: US2009/36534 A1, 2009 ;
Location in patent: Page/Page column 9; 10 ;
反应条件
sodium ethanolate T=20°C; 3 h;
参考文献
Amtul, Zareen; Kausar, Naheed; Follmer, Cristian; Rozmahel, Richard F.; Atta-Ur-Rahman; Kazmi, Syed Arif; Shekhani, Mohammed Saleh; Eriksen, Jason L.; Khan, Khalid M.; Choudhary, Mohammad Iqbal
Bioorganic and Medicinal Chemistry, 2006 , vol. 14, # 19 p. 6737 - 6744
反应条件
(i) BF3-Et2O, AcOH, (ii) aq. NaOAc; Multistep reaction;
参考文献
Zee-Cheng,K.-Y.; Cheng,C.C.
Journal of Medicinal Chemistry, 1970 , vol. 13, p. 414 - 418
反应条件
(i) BF3-Et2O, AcOH, (ii) aq. NaOAc; Multistep reaction;
参考文献
Zee-Cheng,K.-Y.; Cheng,C.C.
Journal of Medicinal Chemistry, 1970 , vol. 13, p. 414 - 418
参考文献
Wang,S.-S.; Carpenter,F.H.
Journal of Organic Chemistry, 1967 , vol. 32, p. 3256 - 3258
