4-(苄氧基)-N,N-二甲基-吲哚-3-乙醛酰胺合成路线 （共 9 条）
参考文献
Nichols, David E.; Frescas, Stewart
Synthesis, 1999 , # 6 p. 935 - 938
反应条件
in diethyl ether; dichloromethane 6 h; Yield given;
参考文献
Sard, Howard; Kumaran, Govindaraj; Morency, Cynthia; Roth, Bryan L.; Toth, Beth Ann; He, Ping; Shuster, Louis
Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 20 p. 4555 - 4559
反应条件
und nachfolgend mit Dimethylamin in Aether.;
参考文献
Hoffmann et al.
Helvetica Chimica Acta, 1959 , vol. 42, p. 1557,1563,1570
反应条件
1: 73 percent / LAH 2: 73 percent / NaH 3: 78 percent / H2 / Pd/C View Scheme
参考文献
Sard, Howard; Kumaran, Govindaraj; Morency, Cynthia; Roth, Bryan L.; Toth, Beth Ann; He, Ping; Shuster, Louis
Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 20 p. 4555 - 4559
反应条件
1: 94.8 percent / LiAlH4 / tetrahydrofuran; dioxane / 1.) 4 h, 2.) reflux, 20 h 2: H2, AcONa / 10 percent Pd/C / benzene / 4 h / 3102.89 Torr View Scheme
参考文献
Nichols, David E.; Frescas, Stewart
Synthesis, 1999 , # 6 p. 935 - 938
反应条件
1: 94.8 percent / LiAlH4 / tetrahydrofuran; dioxane / 1.) 4 h, 2.) reflux, 20 h 2: 97 percent / H2 / 10 percent Pd/C / ethanol / 2 h / 3102.89 Torr View Scheme
参考文献
Hoffmann et al.
Helvetica Chimica Acta, 1959 , vol. 42, p. 1557,1563,1570
反应条件
lithium aluminium tetrahydride in tetrahydrofuran; 1,4-dioxane
1.) 4 h, 2.) reflux, 20 h;
参考文献
Nichols, David E.; Frescas, Stewart
Synthesis, 1999 , # 6 p. 935 - 938
参考文献
Troxler et al.
Helvetica Chimica Acta, 1959 , vol. 42, p. 2073,2098
反应条件
1: 94.8 percent / LiAlH4 / tetrahydrofuran; dioxane / 1.) 4 h, 2.) reflux, 20 h
2: 97 percent / H2 / 10 percent Pd/C / ethanol / 2 h / 3102.89 Torr
3: 1.) n-BuLi, iPr2NH, tetra-O-benzyl pyrophosphate, 2.) H2 / 2.) 10 percent Pd/C / 1.) THF, hexane, -78 deg C, 3 min; 1.5 h, 2.) MeOH, 60 psig, 3 h
View Scheme
参考文献
Nichols, David E.; Frescas, Stewart
Synthesis, 1999 , # 6 p. 935 - 938
