4-(2-溴乙基)苯甲酸合成路线 （共 14 条）
反应条件
sulfuric acid in dichloromethane 24 h; Ambient temperature;
参考文献
Taylor, Edward C.; Young, Wendy B.
Journal of Organic Chemistry, 1995 , vol. 60, # 24 p. 7947 - 7952
反应条件
1: (COBr)2
2: NaN3 / dimethylsulfoxide
3: H2 / Raney Ni / ethanol / 20 °C / 760 Torr
View Scheme
参考文献
Elworthy, Todd R.; Brill, Emma R.; Chiou, San-San; Chu, Frances; Harris, Jason R.; Hendricks, R. Than; Huang, Jane; Kim, Woongki; Lach, Leang K.; Mirzadegan, Tara; Yee, Calvin; Walker, Keith A. M.
Journal of Medicinal Chemistry, 2004 , vol. 47, # 25 p. 6124 - 6127
反应条件
1: 88 percent / H2SO4 / CH2Cl2 / 24 h / Ambient temperature
2: 8 percent / NaH / dimethylformamide / 1.) 0 deg C, 20 min, 2.) 0 deg C, 2 h
View Scheme
参考文献
Taylor, Edward C.; Young, Wendy B.
Journal of Organic Chemistry, 1995 , vol. 60, # 24 p. 7947 - 7952
反应条件
1: 71 percent / methanol; H2O / 7 h / Heating
2: SO2Cl / benzene / 2 h / Heating
View Scheme
参考文献
Delia, Thomas J.; Baumann, Markus; Bunker, Amy
Heterocycles, 1993 , vol. 35, # 2 p. 1397 - 1410
