N-(4-甲硫基-丁基)邻苯二甲酰亚胺合成路线 （共 18 条）
反应条件
1: 21.1 mmol / hydrazine monohydrate; hydrogen chloride / ethanol / 2 h / 75 °C 2: 12.5 mmol / sodium hydroxide / CHCl3 3: 100 percent / m-chloroperbenzoic acid / CH2Cl2 / 0.5 h View Scheme
参考文献
Rajski, Scott R.; Mays, Jared Rae
Patent: US2013/116203 A1, 2013 ;
反应条件
1: 21.1 mmol / hydrazine monohydrate; hydrogen chloride / ethanol / 2 h / 75 °C 2: 12.5 mmol / sodium hydroxide / CHCl3 View Scheme
参考文献
Schmid; Karrer
Helvetica Chimica Acta, 1948 , vol. 31, p. 1497,1500
反应条件
hydrazine in ethanol 3 h; Heating / reflux;
参考文献
Rajski, Scott R.; Mays, Jared Rae
Patent: US2013/116203 A1, 2013 ;
Location in patent: Paragraph 0090 ;
反应条件
1: hydrazine 3: aq. ethanol / 48 h / 27 °C / Helminthosporium species NRRL 4671 View Scheme
参考文献
Holland, Herbert L.; Brown, Frances M.; Larsen, Brett G.; Zabic, Mirjana
Tetrahedron: Asymmetry, 1995 , vol. 6, # 7 p. 1569 - 1574
反应条件
Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Schenk, Wolfdieter A.; Duerr, Michael
Chemistry - A European Journal, 1997 , vol. 3, # 5 p. 713 - 716
反应条件
1: hydrazine 3: aq. ethanol / 48 h / 27 °C / Helminthosporium species NRRL 4671 View Scheme
参考文献
Holland, Herbert L.; Brown, Frances M.; Larsen, Brett G.; Zabic, Mirjana
Tetrahedron: Asymmetry, 1995 , vol. 6, # 7 p. 1569 - 1574
反应条件
Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Schenk, Wolfdieter A.; Duerr, Michael
Chemistry - A European Journal, 1997 , vol. 3, # 5 p. 713 - 716
反应条件
dihydrogen peroxide in ethanol; water; acetic acid T=0 - 20°C;
参考文献
PharmAgra Labs, Inc.
Patent: US2008/176942 A1, 2008 ;
Location in patent: Page/Page column 8 ;
反应条件
water; dihydrogen peroxide; acetone
参考文献
Schmid; Karrer
Helvetica Chimica Acta, 1948 , vol. 31, p. 1497,1500
反应条件
1: hydrazine hydrate / ethanol / 3 h / |Reflux
2: sodium hydroxide / dichloromethane / 3.5 h / 0 - 20 °C / |Inert atmosphere
3: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 2 h / |Inert atmosphere
View Scheme
参考文献
Rajski, Scott R.; Mays, Jared Rae
Patent: US2013/116203 A1, 2013 ;
